文献类型：期刊文献

英文题名：Water-based DNF@PLA microcapsules with excellent interface properties enhancing insecticidal activity against Nilaparvata lugens

作者：Qin, Chen[1];Gao, Yue[1];Zhang, Bo[2];Zhou, Cong[1];Sun, Li[1];Zou, Aihua[2];Cheng, Jiagao[1,3]

机构：[1]East China Univ Sci & Technol, Sch Pharm, State Key Lab Bioreactor Engn, Shanghai Key Lab Chem Biol, Shanghai 200237, Peoples R China;[2]Shanghai Normal Univ, Coll Chem & Mat Sci, Shanghai 200234, Peoples R China;[3]East China Univ Sci & Technol, Sch Biotechnol, Shanghai, Peoples R China

年份：2026

外文期刊名：PEST MANAGEMENT SCIENCE

收录：;Scopus(收录号：2-s2.0-105045198840);WOS:【SCI-EXPANDED(收录号:WOS:001820514900001)】；

基金：The authors gratefully acknowledge the financial support from the National Key Research and Development Program (2022YFD1700501).

语种：英文

外文关键词：dinotefuran; insecticidal activity; interfacial properties; microcapsules; W/O emulsion

摘要：BACKGROUND Dinotefuran (DNF) is a third-generation neonicotinoid and renders broad-spectrum efficacy against piercing-sucking pests. Among these, Nilaparvata lugens, one of the most destructive piercing-sucking pests, is highly susceptible to DNF. However, traditional DNF formulations tend to leach out and exhibit a low utilization rate. This work developed microcapsules using water-in-oil (W/O) emulsions as templates in combination with the eco-friendly material polylactide (DNF@PLA).RESULTS This study employed a variable-controlled method to prepare DNF@PLA. The drug loading and encapsulation efficiency of DNF@PLA were 11.13% and 77.52%, respectively. Compared to commercial suspension agent (SC), DNF@PLA exhibited excellent temperature responsiveness and a 30% improvement in photodegradation resistance. The DNF@PLA exhibited superior control efficacy against Nilaparvata lugens (LC50 = 0.397 mg L-1) than the commercial SC (LC50 = 0.646 mg L-1).CONCLUSION This study demonstrated that DNF@PLA exhibited superior interfacial properties and insecticidal efficacy, enabling reduced surfactant requirements and promising practical applications.