文献类型：期刊文献

英文题名：Eco-toxicological effect of Carbamazepine on Scenedesmus obliquus and Chlorella pyrenoidosa

作者：Zhang, Wei[1,2];Zhang, Meng[1,2];Lin, Kuangfei[1,2];Sun, Wenfang[1,2];Xiong, Bang[1,2];Guo, Meijin[3];Cui, Xinhong[4];Fu, Rongbing[5]

机构：[1]E China Univ Sci & Technol, Sch Resource & Environm Engn, Shanghai Key Lab Funct Mat Chem, Shanghai 200237, Peoples R China;[2]E China Univ Sci & Technol, State Environm Protect Key Lab Environm Risk Asse, Shanghai 200237, Peoples R China;[3]E China Univ Sci & Technol, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China;[4]Shanghai Inst Landscape Gardening, Shanghai 200233, Peoples R China;[5]Shanghai Acad Environm Sci, Shanghai 200233, Peoples R China

年份：2012

卷号：33

期号：2

起止页码：344

外文期刊名：ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000301475000028)】；

基金：This research was financially supported by the National Natural Science Foundation of China (40901148, 40871223, 20807028), the Major State Basic Research Development Program of China (2011CB200904), the Scientific Project on Treatment and Control of Water Pollution (2012ZX07115), the National Forestry Public Welfare Science and Technology Research Program of China (201104088), and the Fundamental Research Funds for the Central Universities (WB0911011). We also would like to thank the anonymous referees for their helpful comments on this paper.

语种：英文

外文关键词：Carbamazepine; Algae; Acute toxicity; Chronic toxicity

摘要：The acute and chronic toxicological effects of Carbamazepine (CBZ) on Scenedesmus obliquus and Chlorella pyrenoidosa were explored for the first time in this study. The results showed that CBZ could significantly inhibit the growth of the two algae in almost all treatment groups. EC50 values indicated that, CBZ had a relatively limited acute toxic effect (0-144h) on S. obliquus and C. pyrenoidosa, while, chronic tests (5-30 d) displayed higher toxicity. Chlorophyll a syntheses were nearly all inhibited by CBZ exposure. However, superoxide dismutase (SOD) and catalase (CAT) activities in acute tests of both algae were markedly promoted. According to the results, Chlorophyll a content and CAT activity of S. obliquus were more sensitive to CBZ than that of C. pyrenoidosa. While for SOD, quite to the contrary, C. pyrenoidosa was more vulnerable. We obtained a similar result in chronic tests. This research furthers our understanding of CBZ toxicity to aquatic organisms. (C) 2012 Elsevier B.V. All rights reserved.