文献类型：期刊文献

英文题名：Photoredox/Nickel Dual-Catalytic Asymmetric Silylarylation of Alkenes

作者：Yuan, Qiyang[1,2];Deng, Zhengrong[1,2];Wan, Yi[1,2];Zhang, Yongqiang[1,2]

机构：[1]East China Univ Sci & Technol, Shanghai Frontiers Sci Ctr Optogenet Tech Cell Met, Shanghai Key Lab New Drug Design, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China

年份：2025

卷号：27

期号：2

起止页码：680

外文期刊名：ORGANIC LETTERS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:001391299800001)】；

基金：Financial support from the program of the National Natural Science Foundation of China (22171080, Y.-Q.Z.) and Natural Science Foundation of Shanghai Municipality (23ZR1417200, Y.-Q.Z.) is gratefully acknowledged.

语种：英文

摘要：The efficient construction of chiral aryl-containing organosilicon frameworks via catalytic enantioselective three-component silylarylation of alkenes remains a great challenge. Herein, a photoredox/nickel dual-catalytic asymmetric protocol has been disclosed by using a chiral biimidazoline (BiIM) as the ligand, silylboranes as the silyl radical precursors, aryl bromides as the coupling partners, and morpholine as the promoter. Remarkably, the reaction features mild and green conditions, high reaction efficiency, and excellent enantioselectivity, enabling the facile synthesis of valuable chiral tropic acid and sila-isoflavanone structures.