文献类型：期刊文献

英文题名：Direct synthesis of polysubstituted 2-aminothiophenes by Cu(II)-catalyzed addition/oxidative cyclization of alkynoates with thioamides

作者：Ge, Li-Shi[1];Wang, Zheng-Lin[1];An, Xing-Lan[1];Luo, Xiaoyan[1];Deng, Wei-Ping[1]

机构：[1]E China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab Funct Mat Chem, Shanghai 200237, Peoples R China

年份：2014

卷号：12

期号：42

起止页码：8473

外文期刊名：ORGANIC & BIOMOLECULAR CHEMISTRY

收录：;EI(收录号：20144300122181);WOS:【SCI-EXPANDED(收录号:WOS:000343956000015)，CCR-EXPANDED(收录号:WOS:000343956000015)】；

基金：This work was financially supported by the Fundamental Research Funds for the Central Universities and the Natural Science Foundation of China (no. 21172068).

语种：英文

外文关键词：Copper compounds - Cyclization

摘要：A facile and direct synthetic method was developed for the construction of structurally important 2-aminothiophenes in moderate to excellent yields (up to 91%), via Cu(II)-catalyzed addition/oxidative cyclization of readily available thioamides with alkynoates under an air atmosphere.