文献类型：期刊文献

英文题名：Diversification of Complex Diaryl Ethers via Diaryliodonium Intramolecular Aryl Rearrangement

作者：Liu, Xu[1,2];Wang, Limin[1,2];Wang, Hao-Yang[3];Han, Jianwei[1,2]

机构：[1]East China Univ Sci & Technol, Key Lab Adv Mat, Sch Chem & Mol Engn, Inst Fine Chem, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Inst Fine Chem, Feringa Nobel Prize Scientist Joint Res Ctr, Sch Chem & Mol Engn, Shanghai 200237, Peoples R China;[3]Chinese Acad Sci, Shanghai Inst Organ Chem, Natl Ctr Organ Mass Spectrometry Shanghai, Shanghai 200032, Peoples R China

年份：2023

卷号：88

期号：18

起止页码：13089

外文期刊名：JOURNAL OF ORGANIC CHEMISTRY

收录：;EI(收录号：20233814758564);WOS:【SCI-EXPANDED(收录号:WOS:001061744300001)】；

基金：The work was supported by the Natural Science Foundationof Shanghai (20ZR1413500). We also thank Professor Zhen-Jiang Xu fromSIOC, CAS, for helpful discussions.

语种：英文

外文关键词：Aromatic hydrocarbons - Ethers - Nitrogen compounds

摘要：In this study, we present an efficient site-selective O-arylation method applicable to a broad range of complex arenes involving intramolecular aryl rearrangement. The reaction was facilitated by diaryliodonium salts bearing vicinal trifluoromethanesulfonate (OTf) groups. The procedure was initiated with selective C-H bond activation of arenes, which were then converted into diaryl ethers through nucleophilic aromatic substitution (SNAr). This synthetic method successfully affords complex diaryl ether derivatives, showcasing its practicality for the diversification of functionalized arenes and pharmaceutical agents.