文献类型：期刊文献

英文题名：Realignment of Bottlebrush Segments Induces the Contraction of Individual Polymer Vesicles

作者：Yin, Xiuzhe[1];Song, Qingliang[2];Hou, Wangmeng[1];Zhou, Yingqing[1];Liu, Zhijia[1];Li, Weihua[2];Du, Jianzhong[3,4];Shi, Yi[1];Chen, Yongming[1,5]

机构：[1]Sun Yat Sen Univ, Sch Mat Sci & Engn, Key Lab Polymer Composite & Funct Mat, Minist Educ, Guangzhou 510006, Peoples R China;[2]Fudan Univ, Dept Macromol Sci, State Key Lab Mol Engn Polymers, Key Lab Computat Phys Sci, Shanghai 200438, Peoples R China;[3]East China Univ Sci & Technol, Sch Mat Sci & Engn, Shanghai 200237, Peoples R China;[4]Tongji Univ, Sch Mat Sci & Engn, Dept Polymer Mat, Shanghai 201804, Peoples R China;[5]Henan Univ, Coll Chem & Mol Sci, Kaifeng 475004, Peoples R China

年份：2025

卷号：58

期号：2

起止页码：989

外文期刊名：MACROMOLECULES

收录：;EI(收录号：20250217662784);WOS:【SCI-EXPANDED(收录号:WOS:001392174200001)】；

基金：The authors gratefully acknowledge the financial support from the National Natural Science Foundation of China (Nos. 22071271, 22371313, 22333002, 22303017, 21925505, 22335005), the Innovation Program of Shanghai Municipal Education Commission (2023ZKZD28), the Natural Science Foundation of Guangdong Province (2024A1515011133), and the Fundamental Research Funds for the Central Universities (23yxqntd002).

语种：英文

外文关键词：Conducting polymers - Elastomers - Grafting (chemical) - Linear transformations - Synthesis (chemical)

摘要：The shape transformation of polymer vesicles is of great importance for biorelevant applications as well as for understanding cellular shape adaptation. However, realizing shape transformation in a controlled manner by rationally manipulating the molecular geometry of the building block is still challenging. Herein, we reported a controlled contraction process of individual polymer vesicles via the realignment of bottlebrush segments by using a linear-alt-bottlebrush alternating multiblock copolymer (LBAMBCP) as the building block. The well-defined LBAMBCPs, A50[(xbB) m A50] n (x = 1 and 3 refer to the grafting density, m = 10, 20, and 30, n = 1, 3, and 5), that consisted of the xbB segment of bottlebrush with varied grafting densities (x) of PS branches and the A segment of linear poly[norbornene-oligopoly(ethylene glycol)] (poly(NB-OEG)) were first synthesized. To perform the self-assembly in a selective solvent of poly(NB-OEG) segments, we found that these LBAMBCPs with a high grafting density (x = 3) of PS branches promoted the formation of vesicular structures, and typical hollow vesicles with an average size over 600 nm were produced. It was observed that the vesicles formed by 7- and 11-LBAMBCPs A50[(3bB)10A50] n (n = 3 and 5) could further undergo the contraction of individual vesicles to evolve into compound vesicles with a steady reduction in size by the realignment of bottlebrush segments in the vesicle wall. The contraction process was confirmed to be strongly related to the number and grafting density of bottlebrush segments and could be simply regulated by changing the initial concentration and solvent composition. Overall, we provide a fresh case for the controlled contraction of individual vesicles by manipulating the molecular geometry of the building blocks.