文献类型：期刊文献

英文题名：Dealing with the Foreign-Body Response to Implanted Biomaterials: Strategies and Applications of New Materials

作者：Zhang, Donghui[1];Chen, Qi[2];Shi, Chao[2];Chen, Minzhang[2];Ma, Kaiqian[2];Wan, Jianglin[2];Liu, Runhui[1,2]

机构：[1]East China Univ Sci & Technol, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Frontiers Sci Ctr Materiobiol & Dynam Chem, Res Ctr Biomed Mat,Minist Educ, Key Lab Ultrafine Mat,Sch Mat Sci & Engn, Shanghai 200237, Peoples R China

年份：2021

卷号：31

期号：6

外文期刊名：ADVANCED FUNCTIONAL MATERIALS

收录：;EI(收录号：20204409410712);WOS:【SCI-EXPANDED(收录号:WOS:000581155900001)】；

基金：This work was supported by the National Natural Science Foundation of China for Innovative Research Groups (No. 51621002), the National Natural Science Foundation of China (No. 21774031, 31800801, 21861162010), the Natural Science Foundation of Shanghai (18ZR1410300), the National Key Research and Development Program of China (2016YFC1100401), Program of Shanghai Academic/Technology Research Leader (20XD1421400), Research program of State Key Laboratory of Bioreactor Engineering, the Fundamental Research Funds for the Central Universities (No. 22221818014, 50321041917001).

语种：英文

外文关键词：anti‐ foreign‐ body response; foreign‐ body response; implants; medical devices

摘要：Foreign-body response caused by implanted biomaterials seriously impedes the function of implants and is a major obstacle to the development of implantable biomaterials and medical devices. Recent advances in implantable biomaterials and medical devices have provided strategies to resist the foreign-body response. In this review, the mechanism of the foreign-body response and conventional strategies to mitigate foreign-body response is briefly introduced. Then, three types of promising foreign-body response resisting materials are focused and the advantages, characteristics, and applications of each material are discussed. Finally, prospects are put forward for future development of foreign-body response resisting materials and current challenges that require in-depth study.