文献类型：期刊文献

英文题名：Synthesis of oxa-bridged carbocycles via rhodium/Lewis acid catalyzed [3 + 3] and [4 + 3] cycloadditions of carbonyl ylides with donor–acceptor strained carbocycles

作者：Li, Jiale[1]; Wang, Lingfei[1]; Liu, Pei-Nian[1,2]; Li, Xingguang[1]

机构：[1] Shanghai Key Laboratory of Functional Materials Chemistry, Key Laboratory for Advanced Materials, School of Chemistry and Molecular Engineering, East China University of Science & Technology, Shanghai, 200237, China; [2] State Key Laboratory of Natural Medicines, School of Pharmacy, China Pharmaceutical University, Nanjing, 210009, China

年份：2024

卷号：12

期号：2

起止页码：491

外文期刊名：Organic Chemistry Frontiers

收录：EI(收录号：20244717411352)

语种：英文

外文关键词：Catalysis - Cycloaddition

摘要：A method for cooperative rhodium/Lewis acid-catalyzed [3 + 3] and [4 + 3] cycloadditions of carbonyl ylides with donor–acceptor (D–A) strained carbocycles is described. It affords access to a wide range of structurally diverse oxa-bridged carbocycles with high efficiency and stereoselectivity. This method operates under mild conditions, exhibits good step and atom economy, and can be extended to [3 + 2] cycloadditions with D–A 1,2-dipoles, enabling the construction of oxa-bridged spirocycles. ? the Partner Organisations 2025.