文献类型：期刊文献

英文题名：A practical approach to quantitative analytical surface-enhanced Raman spectroscopy

作者：Xu, Yikai[1,2];Aljuhani, Wafaa[3];Zhang, Yingrui[3];Ye, Ziwei[1,2];Li, Chunchun[3,4];Bell, Steven E. J.[3]

机构：[1]East China Univ Sci & Technol, Frontiers Sci Ctr Materiobiol & Dynam Chem, Sch Chem & Mol Engn, Key Lab Adv Mat, 130 Meilong Rd, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Feringa Nobel Prize Scientist Joint Res Ctr, Frontiers Sci Ctr Materiobiol & Dynam Chem, Sch Chem & Mol Engn, 130 Meilong Rd, Shanghai 200237, Peoples R China;[3]Queens Univ Belfast, Sch Chem & Chem Engn, Belfast BT9 5AG, North Ireland;[4]Univ Shanghai Sci & Technol, Inst Photochem & Photofunct Mat, 516 Jungong Rd, Shanghai 200093, Peoples R China

年份：2025

卷号：54

期号：1

起止页码：62

外文期刊名：CHEMICAL SOCIETY REVIEWS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:001359579100001)】；

基金：Chunchun Li acknowledges the Shanghai Pujiang Program for support (23PJ1409000). Yikai Xu acknowledges the Young Scientist Fund of the National Natural Science Foundation of China (22402060). Ziwei Ye acknowledges the Shanghai Pujiang Program (23PJ1401900) and Shanghai Post-doctoral Excellence Program (2021111) for funding support. Wafaa Aljuhani acknowledges the support of the Ministry of Education in Saudi Arabia. Steven Bell acknowledges support of the Department of the Economy (N.I.), US-Ireland R&D Partnership Grant USI157. The authors would like to thank Prof. He Tian, Prof. Yi Cheng and Prof. Xiang Ma for support.

语种：英文

摘要：Many of the features of SERS, such as its high sensitivity, molecular specificity and speed of analysis make it attractive as an analytical technique. However, SERS currently remains a specialist technique which has not yet entered the mainstream of analytical chemistry. Therefore, this review draws out the underlying principles for analytical SERS and provides practical tips and tricks for SERS quantitation. The aim is to show the readers how to rationally design their SERS experiments to improve quantitation performance. We begin by introducing the three core components in SERS analysis: (1) the enhancing substrate material, (2) the Raman instrument and (3) the processed data that is used to establish a calibration curve. This is followed by discussion of the analytical figures of merit relevant to SERS. In the following sections each of the three essential components in SERS quantitation and how they affect the quality of the analysis are described in more detail using examples from the literature. Finally, we highlight the current challenges in applying SERS to the analysis of complex real-life samples and briefly introduce the state-of-the-art developments on multifunctional substrates, digital SERS and AI-assisted data processing, which will help SERS rise to the challenge of moving out into routine real-world analysis.