文献类型：期刊文献

中文题名：“Xanthene” is a premium bridging group for xanthenoid dyes

作者：Jin Li[1];Mengmeng Zhang[1];Lu Yang[3];Yubing Han[3];Xiao Luo[2];Xuhong Qian[1];Youjun Yang[1]

机构：[1]State Key Laboratory of Bioreactor Engineering,Shanghai Key Laboratory of Chemical Biology,School of Pharmacy,East China University of Science and Technology,Shanghai 200237,China;[2]School of Chemistry and Molecular Engineering,East China Normal University,Shanghai 200062,China;[3]State Key Laboratory of Modem Optical Instrumentation,College of Optical Science and Engineering,Hangzhou 310027,China

年份：2021

卷号：32

期号：12

起止页码：3865

中文期刊名：Chinese Chemical Letters

外文期刊名：中国化学快报（英文版）

收录：CSTPCD;;Scopus;CSCD:【CSCD2021_2022】；PubMed;

基金：financially supported by the National Natural Science Foundation of China (Nos. 21822805, 21908065, 22078098);the Science and Technology Commission of Shanghai Municipality for the Shanghai International Cooperation Program (No. 18430711000);the China Postdoctoral Science Foundation (Nos. 2019M651427, 2020T130197)。

语种：英文

中文关键词：NIR infrared;Xanthene;Carbon rhodamine;Steric protect;Rigidity

摘要：Novel xanthenoid dyes by replacing the central oxygen atom of the xanthene dyes with less electronrich bridging groups have been intensively sought after primarily for their long spectral wavelengths.However, the new scaffolds are likely prone to nucleophilic attack at their central methane carbon, as the result of the reduced electron density of the fluorochromic scaffolds. We envisage that the bridging group may be harnessed to sterically shield the central methane carbon from incoming nucleophiles and render high stability and synthesized xantheno-xanthene dyes. Additionally, the xantheno-bridging group can be modified via electrophilic aromatic substitution to introduce functionalities, e.g., sulfonate groups.