文献类型：期刊文献

中文题名：辛夷、辛夷仁和辛夷外苞片中挥发性成分的比较

英文题名：Comparative study of volatile components of Magnoliae Flos, Magnoliae Flos kernels, and Magnoliae Flos bracts

作者：胡静[1];付志博[1];桑情妮[1];张敏[2];章弘扬[1];胡坪[1]

机构：[1]上海市功能性材料化学重点实验室华东理工大学化学与分子工程学院,上海200237;[2]上海市新药设计重点实验室华东理工大学药学院,上海200237

年份：2019

卷号：50

期号：7

起止页码：1555

中文期刊名：中草药

外文期刊名：Chinese Traditional and Herbal Drugs

收录：CSTPCD;;Scopus;北大核心:【北大核心2017】；CSCD:【CSCD2019_2020】；

语种：中文

中文关键词：辛夷;辛夷仁;挥发性成分;气相色谱质谱联用;主成分分析;萜烯烃类

外文关键词：Magnoliae Flos;kernels of Magnolia Flos;volatile components;GC-MS;principal component analysis;terpene olefins

摘要：目的分析和比较辛夷全花蕾、辛夷仁和辛夷外苞片中挥发性成分的差异,为经典名方中以辛夷仁入药提供理论依据。方法采用水蒸气蒸馏提取挥发油,气相色谱质谱联用(GC-MS)技术测定辛夷和辛夷仁中的挥发性成分,采用谱库检索结合保留指数定性对挥发性成分进行鉴定,用峰面积归一化法计算各成分的相对含量,利用主成分分析(PCA)对数据进行统计处理。结果全花蕾、辛夷仁和辛夷外苞片中挥发油平均含量分别为1.70%、6.79%和0.45%,采用GC-MS共分别鉴定出87、82、85种化合物,主要为萜烯烃类和醇类化合物。以GC-MS数据结合PCA可以很好地区分辛夷的不同部位和不同产地。结论辛夷仁所含挥发性成分种类与辛夷一致,但含量远高于辛夷全花蕾,经典名方以辛夷仁入药具有科学性。
Objective To analyze the volatile components of Magnoliae Flos,Magnoliae Flos kernels,and Magnoliae Flos bracts and compare the differences of these components in order to provide a theoretical basis for the usage of kernels of Magnolia Flos in classical famous prescriptions.Methods The volatile components were extracted by steam distillation and analyzed by gas chromatography-mass spectrometry(GC-MS).The volatile components in different parts of Magnoliae Flos were identified by searching the retention index in the mass spectrometry database.The relative content of volatile components was calculated by peak area normalization method,and the data of GC-MS was further proceeded by principal component analysis(PCA).Results The average volatile components content in Magnoliae Flos,Magnoliae Flos kernels,and Magnoliae Flos bracts was 1.70%,6.79%,and 0.45%,respectively.The numbers of compounds identified by GC-MS in those three different parts were 87,82,and 85,respectively.These compounds mainly included terpene olefins and alcohols type chemicals.PCA method was then applied to process the GC-MS data and distinguish different parts and habitats of Magnoliae Flos.Conclusion The volatile components in the kernels of Magnoliae Flos were generally the same as those of Magnoliea Flos,while the content of which was much higher than those of whole flower bud of Magnoliae Flos.The results indicated that it was rational to use the kernels of Magnolia Flos in classical famous prescriptions.