文献类型：期刊文献

英文题名：Orchestration of dual cyclization processes and dual quenching mechanisms for enhanced selectivity and drastic fluorescence turn-on detection of cysteine

作者：Tong, Hongjuan[1,2];Zhao, Jianhong[1,2];Li, Xiangmin[1,2];Zhang, Yajun[1,2];Ma, Shengnan[1,2];Lou, Kaiyan[1,2];Wang, Wei[1,2,3]

机构：[1]East China Univ Sci & Technol, Shanghai Key Lab New Drug Design, Shanghai Key Lab Chem Biol, Sch Pharm, 130 Meilong Rd, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, State Key Lab Bioengn Reactor, 130 Meilong Rd, Shanghai 200237, Peoples R China;[3]Univ New Mexico, Dept Chem & Chem Biol, Albuquerque, NM 87131 USA

年份：2017

卷号：53

期号：25

起止页码：3583

外文期刊名：CHEMICAL COMMUNICATIONS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000399000100019)】；

基金：The work was supported by East China University of Science and Technology (start-up funds, W. W.), the Fundamental Research Funds for the Central Universities (K. L., WY1213013), the Pujiang Talent Project (K. L., 14PJ1402200), the National Science Foundation of China (No. 21577037, K. L.) and the China 111 Project (Grant B07023, W. W.).

语种：英文

摘要：We reported a new approach to achieve enhanced selectivity with a drastic turn-on fluorescence response for the detection of Cys through dual intramolecular cyclization processes and dual PET and ICT quenching mechanisms by the incorporation of an acrylate and a maleimide group onto two opposite sides of a single coumarin fluorophore.