文献类型：专利

英文题名：Separating 2,3-butanediol from fermentation liquor comprises e.g. fermenting by using sucrose and Serratia marcescens as bacterial strain to obtain fermentation liquor containing 2,3-butanediol, and passing into membrane separation device

作者：CHEN K;JI L;LI Y;WU B;ZHU J;WU Y;LIU J

机构：[1]UNIV EAST CHINA SCI&TECHNOLOGY;[2]UNIV EAST CHINA SCI & TECHNOLOGY

申请号：CN102320922-A

申请日：2011-07-11

公开日：2012-01-18

语种：英文

收录：DERWENT

摘要：NOVELTY - Separating 2,3-butanediol from fermentation liquor comprises e.g. fermenting by using sucrose as a substrate and Serratia marcescens as bacterial strain to obtain fermentation liquor containing 2,3-butanediol, passing the fermentation liquor into a membrane separation device to separate and recover cells and protein in the fermentation liquor and obtain a transparent clear liquor, transferring the transparent clear liquor into a dealcoholization tower, collecting ethanol aqueous solution at the top of dealcoholization tower, and draining propanol aqueous solution. USE - The method is useful for separating 2,3-butanediol from fermentation liquor. ADVANTAGE - The method: is easy to recover and non-corrosive to devices; reduces the amount of solvent up to 30%; reduces energy consumption up to 15%; produces the product with a purity of more than 99.2%; and has short hydrolysis reaction time. DETAILED DESCRIPTION - Separating 2,3-butanediol from fermentation liquor comprises: (i) fermenting by using sucrose as a substrate, and Serratia marcescens as a bacterial strain to obtain a fermentation liquor containing 2,3-butanediol, passing the fermentation liquor into a membrane separation device to separate and recover cells and protein in the fermentation liquor and obtain a transparent clear liquor; (ii) transferring the transparent clear liquor into a dealcoholization tower, collecting ethanol aqueous solution (95 v/v%) at the top of the dealcoholization tower, draining the propanol aqueous solution (83-90%) from the lateral side of the dealcoholization tower, passing the tower kettle liquid of the dealcoholization tower into a reactive extraction unit; (iii) reacting the tower kettle liquid of the dealcoholization tower with 3-6C fatty aldehyde compounds in the presence of a catalyst at 0-70 degrees C for 10 minutes-3 hours, extracting the aqueous phase of 2,3-butanediol and aldehyde by using acetal as an extracting agent, passing the aqueous phase into a wastewater treating unit; (iv) mixing the organic phase with water in a molar ratio of 1:(1.1-1.3) to obtain a mixed solution, transferring the mixed solution into the reaction section of a hydrolysis separation tower, performing hydrolysis separation under the reaction of a catalyst, maintaining the temperature of the reaction section of the hydrolysis separation tower at 70- 135 degrees C and the reflux ratio of the hydrolysis separation tower at 1-5, extracting the 3-6C fatty aldehyde compounds and the extracting agent from the top of the hydrolysis separation tower, feeding into the reactive extraction unit, and recycling to obtaining 2,3-butanediol and acetoin from the side of the reaction section of the hydrolysis separation tower, and concentrating glycerol in the tower kettle of the hydrolysis separation tower; and (v) feeding the mixture of 2,3-butanediol and acetoin into a 2,3-butanediol recovery tower, performing rectification under vacuum of 0.01-0.06 MPa and reflux ratio of 0.5-5, extracting acetoin from the top of the 2,3-butanediol recovery tower to obtain 2,3-butanediol product from the side of the 2,3-butanediol recovery tower, feeding the mixture of 2,3-butanediol enriched by the tower kettle of the 2,3-butanediol recovery tower and glycerol into the hydrolysis separation tower, and separating, where the catalyst in the step (iii) is a strong acid cation exchange resin, perfluorinated sulfonic acid resin, solid-acid catalyst or heteropolyacid, the reactive extraction unit is an extraction tower with theoretical plate number of 1-20, a mixer settler, a stirred tank reactor, and/or a tubular reactor, the hydrolysis separation tower is a packed tower with theoretical plate number of 50-120, or a combination of packed tower and plate tower, the 2,3-butanediol recovery tower is a packed tower or a plate tower with theoretical plate number of 30-120.