文献类型：期刊文献

英文题名：Identification and morphologic and molecular characterization of Cyclospora macacae n. sp from rhesus monkeys in China

作者：Li, Na[1];Ye, Jianbin[1];Arrowood, Michael J.[2];Ma, Jingbo[1];Wang, Lin[1];Xu, Hailing[1];Feng, Yaoyu[1];Xiao, Lihua[2]

机构：[1]E China Univ Sci & Technol, Sch Resources & Environm Engn, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China;[2]Ctr Dis Control & Prevent, Natl Ctr Emerging & Zoonot Infect Dis, Div Foodborne Waterborne & Environm Dis, Atlanta, GA USA

年份：2015

卷号：114

期号：5

起止页码：1811

外文期刊名：PARASITOLOGY RESEARCH

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000352723200018)】；

基金：This work was supported in part by the National Natural Science Foundation of China (31425025 and 31302078), China Postdoctoral Science Foundation (2014 M560310), Open Funding Project of the State Key Laboratory of Veterinary Etiological Biology, Lanzhou, China (SKLVEB2014KFKT008), and Fundamental Research Funds for the Central Universities, China. The findings and conclusions in this report are those of the authors and do not necessarily represent the views of the Centers for Disease Control and Prevention.

语种：英文

外文关键词：Cyclospora; Cyclospora macacae; Rhesus monkeys; SSU rRNA gene

摘要：Cyclospora spp. in nonhuman primates are most closely related to Cyclospora cayetanensis, an emerging human pathogen causing outbreaks of cyclosporiasis in North America. Studies thus far indicate the possible existence of host specificity in Cyclospora spp. In this study, 411 fecal specimens from free-range rhesus monkeys (Macaca mulatta) were collected and examined for Cyclospora by sequence analysis of the small subunit rRNA gene. A novel Cyclospora species was identified in 28 (6.8 %) specimens and named Cyclospora macacae based on morphologic and molecular characterizations. The oocyst of C. macacae is spherical and measures 8.49 +/- 0.55 x 8.49 +/- 0.49 mu m in diameter. Phylogenetic analysis grouped this species together with the other four Cyclospora species infecting primates, including C. cayetanensis in humans, forming a monophyletic group closely related to avian Eimeria species. In addition, C. cayetanensis was detected in one specimen, although whether rhesus monkeys can serve as a natural reservoir host of C. cayetanensis needs further investigation.