文献类型：期刊文献

中文题名：Enantioselective Allylic Amination of Morita-Baylis-Hillman Acetates Catalyzed by Chiral Thiourea-Phosphine

英文题名：Enantioselective Allylic Amination of Morita-Baylis-Hillman Acetates Catalyzed by Chiral Thiourea-Phosphine

作者：Xuan Zhao[1];Tianchen Kang[1];Jie Shen[1];Feng Sha[1];Xinyan Wu[1]

机构：[1]Key Laboratory for Advanced Materials and Institute of Fine Chemicals, East China University of Science and Technology, Shanghai 200237, China

年份：2015

卷号：33

期号：12

起止页码：1333

中文期刊名：Chinese Journal of Chemistry

外文期刊名：中国化学（英文版）

收录：CSTPCD;;Scopus;CSCD:【CSCD2015_2016】；

基金：We are grateful for the financial support from the National Natural Science Foundation of China （Nos. 21242007, 21102043）, Science and Technology Com- mission of Shanghai Municipality （No. 15ZR1409200）, and the Fundamental Research Funds for the Central Universities.

语种：英文

中文关键词：allylic amination;chiral phosphine;enantioselective organocatalysis;Morita-Baylis-Hillman acetate,phthalimide

外文关键词：allylic amination, chiral phosphine, enantioselective organocatalysis, Morita-Baylis-Hillman acetate,phthalimide

摘要：The enantioselective allylic amination of Morita-Baylis-Hillman acetates catalyzed by chiral cyclohexane-based thiourea-phosphine catalysts was investigated. In the presence of 20 mol% rosin-derived thiourea-phosphine 3j, the chiral amines were obtained in up to 88% yield and up to 85% ee.
The enantioselective allylic amination of Morita-Baylis-Hillman acetates catalyzed by chiral cyclohexane-based thiourea-phosphine catalysts was investigated. In the presence of 20 mol% rosin-derived thiourea-phosphine 3j, the chiral amines were obtained in up to 88% yield and up to 85% ee.