文献类型：期刊文献

英文题名：A Highly Sensitive and Selective OFF-ON Fluorescent Sensor for Cadmium in Aqueous Solution and Living Cell

作者：Cheng, Tanyu[1];Xu, Yuifang[1];Zhang, Shenyi[1];Zhu, Weiping[1];Qian, Xuhong[1];Duan, Liping[1]

机构：[1]E China Univ Sci & Technol, Sch Pharm, State Key Lab Bioreactor Engn, Shanghai Key Lab Chem Biol, Shanghai 200237, Peoples R China

年份：2008

卷号：130

期号：48

起止页码：16160

外文期刊名：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

收录：;EI(收录号：20085011776419);WOS:【SCI-EXPANDED(收录号:WOS:000263319800018)】；

基金：This work is supported by the National Natural Science Foundation of China (Grants 20536010, 20746003) and Program of Shanghai Subject Chief Scientist (Grant 07XD14009) and Shanghai Leading Academic Discipline Project (13507) and the National High Technology Research and Development Program of China (863 Program 2006AA10A201). We also thank Professor Wei Wang for the improvements of this paper.

语种：英文

摘要：A highly selective and sensitive OFF-ON fluorescent sensor 1, employing the PET mechanism, was designed and synthesized. It could be used to detect Cd2+ ion in aqueous solution and to image Cd2+ ion in living cells. The fluorescence intensity significantly enhanced about 195-fold and the quantum yield increased almost 100-fold. Moreover the fluorescence intensity of 1 increased linearly with high sensitivity (0-1 mu M) toward Cd2+.