文献类型：期刊文献

英文题名：Recent progress in biomedical applications of titanium dioxide

作者：Yin, Zi Fei[1];Wu, Long[2];Yang, Hua Gui[2];Su, Yong Hua[1]

机构：[1]Second Mil Med Univ, Dept Tradit Chinese Med, Changhai Hosp, Shanghai 200433, Peoples R China;[2]E China Univ Sci & Technol, Sch Mat Sci & Engn, Key Lab Ultrafine Mat, Minist Educ, Shanghai 200237, Peoples R China

年份：2013

卷号：15

期号：14

起止页码：4844

外文期刊名：PHYSICAL CHEMISTRY CHEMICAL PHYSICS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000316007900002)】；

基金：This work was financially supported by National Natural Science Foundation of China (30973968), International Cooperation Project of China (30810103910), New Hundred Talents Program of Shanghai (XBR2011066).

语种：英文

摘要：As one of the most common chemical materials, titanium dioxide (TiO2) has been prepared and widely used for many years. Among all the applications, the biomedical applications of TiO2 have motivated strong interest and intensive experimental and theoretical studies, owing to its unique photocatalytic properties, excellent biocompatibility, high chemical stability, and low toxicity. Advances in nanoscale science suggest that some of the current problems of life science could be resolved or greatly improved through applying TiO2. This paper presents a critical review of recent advances in the biomedical applications of TiO2, which includes the photodynamic therapy for cancer treatment, drug delivery systems, cell imaging, biosensors for biological assay, and genetic engineering. The characterizations and applications of TiO2 nanoparticles, as well as nanocomposites and nanosystems of TiO2, which have been prepared by different modifications to improve the function of TiO2, are also offered in this review. Additionally, some perspectives on the challenges and new directions for future research in this emerging frontier are discussed.