文献类型：期刊文献

英文题名：Efficient and Generic Preparation of Diverse Polyelectrolyte Nanogels by Electrostatic Assembly Directed Polymerization

作者：Ding, Peng;Huang, Jianan;Wei, Cheng;Liu, Wei;Zhou, Wenjuan;Wang, Jiahua;Wang, Mingwei;Guo, Xuhong;Stuart, Martien A. Cohen;Wang, Junyou[1]

机构：[1]East China Univ Sci & Technol, State Key Lab Chem Engn, Shanghai 200237, Peoples R China; East China Univ Sci & Technol, Shanghai Key Lab Multiphase Mat Chem Engn, Shanghai 200237, Peoples R China

年份：2020

卷号：2

期号：6

起止页码：1016

外文期刊名：CCS CHEMISTRY

收录：WOS:【ESCI(收录号:WOS:000794135200014)】；

基金：This study was financially supported by the 1000 Foreign Experts Program (no. WQ20163100341), the Shanghai Municipal Natural Science Foundation (nos. 17ZR1440500 and 18490740100), and the Fundamental Research Funds for the Central Universities (no. 222201714003).

语种：英文

外文关键词：nanogel; polyelectrolyte; electrostatic interaction; template polymerization; scale-up production; soft nanocarrier; nanoreactor

摘要：Nanogels hold promise as soft and functional carriers and nanoreactors, butwhether theywill ever reach the stage of large-scale application depends crucially on efficient productionmethods, and on what interesting properties and functionalities they can have. In particular, nanogels consisting of highly charged polyelectrolyte have not yet been very much explored. Here, the authors present a novel and generic strategy for controlled and efficient synthesis of a large diversity of polyelectrolyte nanogels. The method is based on polymerizing an ionic monomer in the presence of an oppositely charged polyion-neutral diblock copolymer as template, while adding a cross-linker. The growing polymer chains assemble with the template, forming polyion complex micelles, which dissociate upon increasing salt concentration. Subsequent separation yields nanogels with well-controlled size and properties, and free template polymers that can be used again. Our design can be applied generally to a wide range of both cationic and anionicmonomers, as well as various cross-linkers. Scaled-up production presents no problems as increasingmonomer concentration (hundreds of mM) and reaction volume (up to 1 L) hardly compromise product quality. Moreover, the obtained nanogels with their well-controlled size, morphology, chemistry, and cross-linking degree performwell as soft nanocarriers and catalytic nanoreactors.