文献类型：专利

英文题名：Beta-galactosidase fluorescent probe comprises beta-galactosidase derivative or pharmaceutically acceptable salt

作者：ZHU W;GUO Z;GU K;YAN C;WANG S;LI Q;ZHANG J;FU W

机构：[1]UNIV EAST CHINA SCI & TECHNOLOGY

申请号：CN106905389-A

申请日：2017-01-24

公开日：2017-06-30

语种：英文

收录：DERWENT

摘要：NOVELTY - Beta-galactosidase fluorescent probe comprises beta-galactosidase derivative(I) or a pharmaceutically acceptable salt. USE - Beta-galactosidase fluorescent probe. ADVANTAGE - The beta-galactosidase fluorescent probe has strong retention capability after activation in a cell, and the cell beta-galactosidase expression helps in long time (12 hours) imaging. DETAILED DESCRIPTION - Beta-galactosidase fluorescent probe comprises beta-galactosidase derivative represented by formula (I). R1=1-4C is a hydrocarbon, sulfonic acid, or phenyl group; R2, R3 and R4=1-3C is a hydrogen, or hydrocarbon group or a combination; R4=H; and R5=cyano group of formula (II).