文献类型：期刊文献

英文题名：Magnetic microswimmers with infrared-induced shape transformation

作者：Yang, Runhuai[1];Zhu, Shilu[1];Zhang, Lijiu[2];Niu, Fuzhou[3];Liu, Shuang[4]

机构：[1]Anhui Med Univ, Anhui Med Univ Res & Engn, Sch Biomed Engn, Ctr Biomed Mat, Hefei 230032, Peoples R China;[2]Anhui Med Univ, Dastroenterol Dept, Affiliated Hosp 2, Hefei 230601, Peoples R China;[3]Suzhou Univ Sci & Technol, Sch Mech Engn, Suzhou 215009, Peoples R China;[4]East China Univ Sci & Technol, Sch Mech & Power Engn, Shanghai 200237, Peoples R China

年份：2021

卷号：16

期号：12

起止页码：582

外文期刊名：MICRO & NANO LETTERS

收录：;EI(收录号：20213010674669);WOS:【SCI-EXPANDED(收录号:WOS:000703009500001)】；

基金：This work was supported by the National Natural Science Foundation of China (Project No. 61973003, 61603002, 51975214, 61903269). the Key Program in the Youth Elite Support Plan in Universities of Anhui Province (gxyqZD2020012), the Basic and Clinical Collaborative Research Improvement Project of Anhui Medical University (2019xkjT017), and the Natural Science Foundation of Jiangsu Province under Grant BK20190941, and the China Postdoctoral Science Foundation under Grant 2020M681517, and the Postdoctoral Science Foundation of Jiangsu Province under Grant 2020Z063.

语种：英文

外文关键词：Magnetism - Fabrication

摘要：Soft untethered microswimmers have recently been demonstrated to be capable of transporting and delivering cargos by external control while maintaining biocompatibility and safety. However, such microswimmers still suffer from complex and inconvenient fabrication processes and control methods, which impedes their clinical translation. In this paper, an easy-to-fabricate, magnetic-driven and IR-induced shape transformative microswimmer is presented. This microswimmer can be fabricated in a fast, low-cost and high-throughput manner. Besides, the soft body of the microswimmer can provide an inherent friendly contact with the biological environment, and its components are biocompatible and biodegradable. Being magnetically-drivable allows the microswimmer to provide untethered movement and targeted therapy in the human body, and its IR-induced shape transformability enables penetrable regulation of the movement and function. Furthermore, the shape of the untethered microswimmer can be transformed due to its combination of low melting behaviours and multi-response materials, suggesting that other materials with similar properties can also be adopted in a similar method. The proposed method validates the feasibility to integrate polymers for fabricating magnetic-driven, infrared-responsive and shape transformative microswimmers.