文献类型：期刊文献

英文题名：Incorporation of molybdenum disulfide into polyetheretherketone creating biocomposites with improved mechanical, tribological performances and cytocompatibility for artificial joints applications

作者：Lv, Xinke[1];Wang, Xuehong[1];Tang, Songchao[1];Wang, Dongliang[2];Yang, Lili[3];He, Axiang[3];Tang, Tingting[4];Wei, Jie[1]

机构：[1]East China Univ Sci & Technol, Key Lab Ultrafine Mat, Minist Educ, Shanghai 200237, Peoples R China;[2]Shanghai Jiao Tong Univ, Xin Hua Hosp, Dept Orthoped Surg, Sch Med, 1665 Kongjiang Rd, Shanghai 200092, Peoples R China;[3]Second Mil Med Univ, Changzheng Hosp, Dept Orthopaed Surg, Shanghai 200003, Peoples R China;[4]Shanghai Jiao Tong Univ, Shanghai Peoples Hosp 9, Dept Orthopaed Surg, Shanghai Key Lab Orthopaed Implants,Sch Med, Shanghai 200011, Peoples R China

年份：2020

卷号：189

外文期刊名：COLLOIDS AND SURFACES B-BIOINTERFACES

收录：;EI(收录号：20200508111132);WOS:【SCI-EXPANDED(收录号:WOS:000527314700008)】；

基金：The work was financial supported by the National key research and development program (2016YFC1102100), the National Natural Science Foundation of China (81771990 and 81572194), Key Medical Program of Science and Technology Development of Shanghai (19441906100,17441900600 and 17441902000), and the Opening Project of Shanghai Key Laboratory of Orthopaedic Implants.

语种：英文

外文关键词：Polyetheretherketone; Molybdenum disulfide; Mechanical performances; Tribological performances; Cytocompatibility

摘要：To improve mechanical, tribological and biological performances of polyetheretherketone (PEEK) for artificial joints applications, molybdenum disulfide (MoS2, MS) nanosheets were incorporated into PEEK to fabricate MS/ PEEK biocomposites (MPC) with MS content of 4w% (MPC4) and 8w% (MPC8). The results revealed that the MS nanosheets with the size of about 400 nm and sheet thickness of about 70 nm were distributed into PEEK matrix, and surface roughness as well as hydrophilicity of MPC increased with the MS content increasing. Moreover, the compressive strength and shore hardness of the MPC were accordingly enhanced. Furthermore, the coefficient of friction of the MPC decreased while the wear resistance of the MPC increased with the MS content increasing in both water-sliding and dry-sliding contact. In addition, rat bone marrow derived stromal cells adhered and proliferated on the composites, indicating that the MPC had no adverse influences on cell behaviors, indicating good cytocompatibility. The results demonstrated that incorporation of MS nanosheets into PEEK produced biocomposites with improved mechanical, tribological and biological performances. MPC8 with no cytotoxicity would have a great potential for artificial joints applications.