文献类型：期刊文献

英文题名：CuI-catalyzed intramolecular cyclization of 3-(2-aminophenyl)-2-bromoacrylate: synthesis of 2-carboxyindoles

作者：Xiao, Xiong[1];Chen, Tian-Qi[1];Ren, Jiangmeng[1];Chen, Wei-Dong[3];Zeng, Bu-Bing[1,2,3]

机构：[1]E China Univ Sci & Technol, Shanghai Key Lab New Drug Design, Sch Pharm, Shanghai 200237, Peoples R China;[2]Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Synthet Chem Nat Subst, Shanghai 200032, Peoples R China;[3]E China Univ Sci & Technol, Shanghai Key Lab Chem Biol, Shanghai 200237, Peoples R China

年份：2014

卷号：55

期号：13

起止页码：2056

外文期刊名：TETRAHEDRON LETTERS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000333792000002)，CCR-EXPANDED(收录号:WOS:000333792000002)】；

基金：We are grateful for the financial support by The Fundamental Research Funds for the Central Universities (WY1113007).

语种：英文

外文关键词：Indoles; CuI-catalyzed; Intramolecular coupling; 2-Bromo-3-phenylacrylate

摘要：A new approach was described for the synthesis of substituted 2-carboxyindole using 3-(2-aminophenyl)-2-bromo-acrylates through a CuI-catalyzed intramolecular coupling. The reactions were mild, rapid and with good to excellent yields. Crown Copyright (C) 2013 Published by Elsevier Ltd. All rights reserved.