文献类型：期刊文献

中文题名：Design, synthesis and insecticidal activity of biphenyl-diamide derivatives

英文题名：Design, synthesis and insecticidal activity of biphenyl-diamide derivatives

作者：Ye Liu[1];Chao Lei[1];Xiao-Yong Xu[1];Xu-Sheng Shao[1];Zhong Li[1]

机构：[1]Shanghai Key Laboratory of Chemical Biology,School of Pharmacy,East China University of Science and Technology

年份：2016

卷号：27

期号：3

起止页码：321

中文期刊名：Chinese Chemical Letters

外文期刊名：中国化学快报（英文版）

收录：CSTPCD;;Scopus;CSCD:【CSCD2015_2016】；PubMed;

语种：英文

中文关键词：Diamide Insecticide Ryanodine insecticide Biphenyl

外文关键词：Diamide Insecticide Ryanodine insecticide Biphenyl

摘要：Diamides acting on insect ryanodine receptors are an intensive research area now. In order to search for novel candidates, a series of diamides containing biphenyl substructure were designed and synthesized.Their insecticidal activities against armyworms（Mythimna sepatara） and aphis（Aphis craccivora） were screened. The compounds with 3,5-dichloro-4-（1,1,2,2-tetrafluoroethoxy）phenyl substituent were found to be insecticidal to armyworms with the similar symptoms to poisoning by flubendiamide. In this research, we presented a novel type of diamide insecticide as a lead compound for further optimization.
Diamides acting on insect ryanodine receptors are an intensive research area now. In order to search for novel candidates, a series of diamides containing biphenyl substructure were designed and synthesized.Their insecticidal activities against armyworms（Mythimna sepatara） and aphis（Aphis craccivora） were screened. The compounds with 3,5-dichloro-4-（1,1,2,2-tetrafluoroethoxy）phenyl substituent were found to be insecticidal to armyworms with the similar symptoms to poisoning by flubendiamide. In this research, we presented a novel type of diamide insecticide as a lead compound for further optimization.