文献类型：期刊文献

英文题名：Gold-Catalyzed Fluorination-Hydration: Synthesis of -Fluorobenzofuranones from 2-Alkynylphenol Derivatives

作者：Wang, Qiang[1,2];Jiang, Yu[1,2];Sun, Run[1,2];Tang, Xiang-Ying[3];Shi, Min[1,2,3]

机构：[1]East China Univ Sci & Technol, Key Lab Adv Mat, Sch Chem & Mol Engn, Meilong Rd 130, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Inst Fine Chem, Sch Chem & Mol Engn, Meilong Rd 130, Shanghai 200237, Peoples R China;[3]Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, 345 Lingling Rd, Shanghai 200032, Peoples R China

年份：2016

卷号：22

期号：41

起止页码：14739

外文期刊名：CHEMISTRY-A EUROPEAN JOURNAL

收录：;EI(收录号：20163902857693);WOS:【SCI-EXPANDED(收录号:WOS:000384698500045)，CCR-EXPANDED(收录号:WOS:000384698500045)】；

基金：We are grateful for financial support from the National Basic Research Program of China (973)-2015CB856603 and the National Natural Science Foundation of China (20472096, 21372241, 21361140350, 20672127, 21421091, 21102166, 21121062, 21302203, 20732008, and 21572052). We also thank Dr. Haoyang Wang from SIOC for performing the mass spectroscopy measurements.

语种：英文

外文关键词：alkynes; fluorine; gold; hydration; Selectfluor

摘要：The Au-I-catalyzed fluorination-hydration of 2-alkynylphenol derivatives in the presence of Selectfluor [1-chloromethyl-4-fluoro-1,4-diazoniabicyclo-[2.2.2]octane bis(tetrafluoroborate)] has been developed. This method provides straightforward access to -fluorobenzofuranones with the construction of C-O, C=O, and C-F bonds in a single step on the basis of an Au-I/Au-III redox catalytic cycle. Several control experiments, including the asymmetric variant of this reaction, were also conducted to gain insight into the reaction mechanism.