文献类型：期刊文献

中文题名：以柠檬酸作交联剂改善丝胶/聚乙烯醇热固化膜的性能

英文题名：Improvement of Film-forming Property of Sericin/Polyvinyl Alcohol Molded Under High Temperature by Using Citric Acid as Cross-linking Agent

作者：高洋[1];冯屏[2];田晓慧[1];闫伟[2]

机构：[1]华东理工大学材料科学与工程学院,上海200237;[2]华东理工大学生物工程学院,上海200237

年份：2010

卷号：36

期号：1

起止页码：91

中文期刊名：蚕业科学

外文期刊名：ACTA SERICOLOGICA SINICA

收录：CSTPCD;;北大核心:【北大核心2008】；CSCD:【CSCD_E2011_2012】；

基金：上海市基础研究重点项目(No.09JC1404300)

语种：中文

中文关键词：丝胶;聚乙烯醇;柠檬酸;交联;干燥温度;力学性能;溶失率;细胞毒性

外文关键词：Sericin Polyvinyl alcohol Citric acid Cross-linking Drying temperature Mechanical property Dissolution rate Cytotoxicity

摘要：交联、接枝和共混等是改善纯丝胶膜耐溶失与力学性能的重要技术方法。以柠檬酸作为交联剂制备的丝胶/聚乙烯醇/柠檬酸共混固化膜的表面结构形态得到改善,耐溶失性能以及力学性能显著提高。成膜条件对丝胶/聚乙烯醇/柠檬酸共混固化膜结构及其性能产生影响,适当升高干燥温度有助于提高柠檬酸与丝胶和聚乙烯醇的交联程度,在干燥温度为120℃、柠檬酸质量分数为0.6%的条件下,制备的共混固化膜表现出最佳的力学性能和耐溶失性能。用柠檬酸作交联剂的丝胶/聚乙烯醇/柠檬酸共混固化膜材料培养L929细胞,测试其对细胞毒性的分级为一级(细胞为圆形,偶见裂解细胞),具有良好的生物医用价值。
Cross-linking,grafting and blending are important technological measures to improve dissolution-resistant and mechanical properties of the pure sericin film.With citric acid as the cross-linking agent,surface structure of the sericin/PVA/citric acid solidified film could be further improved,and dissolution-resistant and mechanical properties of the film could be enhanced significantly.Film-forming conditions had an impact on structure and property of the sericin/PVA/citric acid solidified film.An adequately increased drying temperature was favorable to increase the cross-linking degree between citric acid and polyvinyl alcohol.When the drying temperature was 120 ℃ and the mass fraction of citric acid was 0.6%,the obtained film showed the best mechanical and dissolution-resistant properties.Toxicity test with L929 cells showed that the sericin/PVA/citric acid solidified film prepared with citric acid as the cross-linking agent was in line with the first grade in the grading of cytotoxicity（with round cells and occasionally lysed cells）,having promising biomedical values.