文献类型：专利

英文题名：Antibiosis hemostatic granule used for stopping bleeding or for maintaining hemostatic effect, comprises silver and mesoporous silicon dioxide, where the silver is uniformly distributed in inner framework of the mesoporous silicon dioxide

作者：HONG H;LIU C;WANG C;YUAN Y

机构：[1]UNIV EAST CHINA SCI & TECHNOLOGY

申请号：CN104147633-B

公开日：2016-08-31

语种：英文

收录：DERWENT

摘要：NOVELTY - Antibiosis hemostatic granule comprises silver and mesoporous silicon dioxide, where the silver is uniformly distributed in inner framework of the mesoporous silicon dioxide, and average grain daimeter of granules are 450-700 mu m. USE - Antibiosis hemostatic granule used for stopping bleeding or for maintaining hemostatic effect. ADVANTAGE - The antibiosis hemostatic granule is prepared in simple and cost-effective manner, and is easily stored and easy in transportation. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for a method for preparing antibiosis hemostatic granule, which involves: (A) dissolving surface active agent in polar solvent, and then adding silicon and silver sources at pH 2-10 to obtain a sol by sol-gel process; (B) aging the obtained sol, and drying them to obtain a silver-containing hemostatic powder; and (C) adding binder to the obtained material, and then granulating them to obtain finished product, where the silver source is silver nitrate, silver acetate or silver phosphate or their combination, and the silicon source is ethyl orthosilicate, methyl silicate, water glass or their combination, and surface active agent is selected from alkyl trimethylamine, polyoxyethylene alkyl ether with 8-20C alkyl, block polymer of ethanediol and propylene glycol, hexadecyltrimethylammonium bromide, sodium dodecylbenzenesulfonate or polyethylene oxide-polypropylene oxide-polyethylene oxide tri-block copolymer, and polar solvent is selected form water, alcohol, ether, ketone or their mixture, and additives are selected form starch, dextrin, gelatin, polyvinyl alcohol, carboxymethyl cellulose, polyvinylpyrrolidone or their combination, and adhesive material is selected form a natural clay, silica sol, bentonite, carboxymethyl cellulose, humic acid or their combination.