文献类型：期刊文献

英文题名：Fabricating carbon-nanotubes-based porous foam for superoxide electrochemical sensing through one-step hydrothermal process induced by phytic acid

作者：Cai, Xuan[1];Chen, Kaicha[1];Wang, Zhenxing[1];Sun, Wenqian[1];Zhao, Hongli[1];Zhang, Huanhuan[1];Chen, Huilan[1];Lan, Minbo[1,2]

机构：[1]East China Univ Sci & Technol, Sch Chem & Mol Engn, Shanghai Key Lab Funct Mat Chem, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China

年份：2018

卷号：1038

起止页码：132

外文期刊名：ANALYTICA CHIMICA ACTA

收录：;EI(收录号：20182905547718);WOS:【SCI-EXPANDED(收录号:WOS:000445895500016)】；

基金：This research was financially supported by the Science and Technology Commission of Shanghai Municipality (STCSM, No. 16520710800) and the Fundamental Research Funds for the Central Universities (No. 222201817022).

语种：英文

外文关键词：Carbon nanotubes; 3D porous foam; Cuperoxide anion; Living cells; Electrochemical sensor

摘要：The detection of superoxide anions (O-2(center dot-)) is widely considered as a potential way for cancer diagnosis and the development of enzyme-mimic catalysts is the main challenge in the establishment of electrochemical sensors for O-2(center dot-) sensing in real samples. Here we present a novel enzyme- and metal-free electrochemical catalyst for superoxide (O-2(center dot-)) sensing based on the widely-used carbon nanotubes (CNT). Through a one-step hydrothermal process induced by phytic acid (PA), CNT-based porous foam (PACNTF) was successfully obtained. Characterizations demonstrated the enhanced defect and disorder degree of PACNTF after PA treatment, which leaded to the increased active sites of PACNTF for electron transfer and the adhesion of O-2(center dot-) during the electrochemical process. As a result, the PACNTF presented higher conductivity and larger current response toward O-2(center dot-) sensing when compared with CNT precursor and CNTF without PA treatment. The sensitivity of PACNTF/SPCE was calculated to be 1230 mu A cm(-2) mM(-1) in the linear range of 0-193.6 mu M(R-2 = 0.965) and 373 mu A cm(-2) mM(-1) in the linear range of 193.6-1153.6 mu M(R-2 = 0.995) with a limit of detection of 0.16 mu M(S/N = 3). Further, the PACNTF/SPCE presented fast response toward cell-released O-2(center dot-) stimulated by Zymosan A. The above results indicated that the fabricated sensor holds potential usage in biological samples. (C) 2018 Elsevier B.V. All rights reserved.