文献类型：期刊文献

中文题名：红霉素组分在C18柱上热力学和动力学研究

英文题名：THERMODYNAMICS AND KINETICS OF ERYTHROMYCIN ON C18 COLUMN

作者：刘斌杰[1];陈葵[1];朱家文[1];武斌[1];纪利俊[1];吴艳阳[1]

机构：[1]华东理工大学化学工程研究所,上海200237

年份：2020

期号：3

起止页码：211

中文期刊名：离子交换与吸附

外文期刊名：Ion Exchange and Adsorption

收录：CSTPCD;;Scopus;北大核心:【北大核心2017】；

基金：上海市科委项目(18595800900)

语种：中文

中文关键词：红霉素;竞争吸附;传质系数;温度

外文关键词：Erythromycin;Competitive adsorption;Mass transfer coefficient;Temperature

摘要：为研究红霉素A (EA)和红霉素C (EC)在色谱柱上的色谱分离过程,采用吸附脱附法,测定了不同温度下EA和EC在C18柱上的吸附量,获得了EA和EC在吸附剂上的吸附平衡参数,并发现EA和EC存在竞争吸附关系。通过建立传质扩散模型拟合不同温度下EA和EC在色谱柱上的吸附分离过程,得到传质系数与温度的关系。然后通过比较模型拟合结果与吸附脱附实验值,验证了所得参数的准确性与可靠性。
The chromatographic separation process of erythromycin A(EA) and erythromycin C(EC) on C18 column was studied. The adsorption capacity of EA and EC on C18 column at different temperatures was determined by adsorption-desorption method. The equilibrium parameters were obtained and found that EA and EC had competitive adsorption relationship. By establishing the transport model to fit the adsorption separation process of EA and EC on the column at different temperature, the relationship between mass transfer coefficient and temperature was obtained. Then the accuracy and reliability of the obtained parameters were verified by comparing the model fitting results with the adsorption desorption experiments.