文献类型：期刊文献

英文题名：Partition behavior of spiramycin in an aqueous two-phase system based on polyethylene glycol and sulfates

作者：Li, Yajuan[1];Wu, Yanyang[1];Chen, Kui[1];Wu, Bin[1];Ji, Lijun[1];Zhu, Jiawen[1]

机构：[1]East China Univ Sci & Technol, Chem Engn Res Ctr, Shanghai 200237, Peoples R China

年份：2018

卷号：53

期号：3

起止页码：496

外文期刊名：SEPARATION SCIENCE AND TECHNOLOGY

收录：;EI(收录号：20174904502894);WOS:【SCI-EXPANDED(收录号:WOS:000418081800009)】；

基金：Financial support from Shanghai Pujiang Program (NO. 16PJD019) is gratefully acknowledged.

语种：英文

外文关键词：Partition behavior; spiramycin; polymer-salt aqueous two-phase system

摘要：A polymer-salt aqueous two-phase system based on polyethylene glycol and sulfates was applied to explore the partition behavior of spiramycin. Binodal curves were measured by the turbidimetric titration method. The influence of temperature, salt concentration, and pH on the distribution behavior was investigated in detail by determining the partition coefficient and extraction efficiency. As pH and salt concentration increase, the partition coefficients increase accordingly. It was found that pH displays a significant influence on the partition behavior. The partition coefficient and extraction efficiency can reach 42.46 and 97.8%, respectively, at pH 9.0 and 15.80% (w/w) salt concentration.