文献类型：期刊文献

英文题名：Peptide self-assembly triggered by metal ions

作者：Zou, Rongfeng[1,2];Wang, Qi[3];Wu, Junchen[1,2];Wu, Jingxian[1,2];Schmuck, Carsten[4];Tian, He[1,2]

机构：[1]E China Univ Sci & Technol, Key Lab Adv Mat, Shanghai 200237, Peoples R China;[2]E China Univ Sci & Technol, Inst Fine Chem, Shanghai 200237, Peoples R China;[3]Nantong Univ, Coll Publ Hlth, Nantong 226019, Peoples R China;[4]Univ Duisburg Essen, Inst Organ Chem, D-45117 Essen, Germany

年份：2015

卷号：44

期号：15

起止页码：5200

外文期刊名：CHEMICAL SOCIETY REVIEWS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000358219300011)】；

基金：We thank the National Basic Research 973 Program (2013CB733700), the Fundamental Research Funds for the Central Universities (WJ1213007), the Program of Shanghai Pujiang (K100-2-1275), the Innovation Program of Shanghai Municipal Education Commission (J100-2-13104), and the National Natural Science Foundation of China (21341001) for financial support.

语种：英文

摘要：Through their unique and specific interactions with various metal ions, naturally occurring proteins control structures and functions of many biological processes and functions in organisms. Inspired by natural metallopeptides, chemists have developed artificial peptides which coordinate with metal ions through their functional groups either for introducing a special reactivity or for constructing nano-structures. However, the design of new coordination peptides requires a deep understanding of the structures, assembly properties, and dynamic behaviours of such peptides. This review briefly discusses strategies of peptide self-assembly induced by metal coordination to different natural and non-natural binding sites in the peptide. The structures and functions of the obtained aggregates are described as well. We also highlight some examples of a metal-induced peptide self-assembly with relevance to biotechnology applications.