文献类型：期刊文献

英文题名：Silica based click amino stationary phase for ion chromatography and hydrophilic interaction liquid chromatography

作者：Liu, Yajing[1];Du, Qing[1];Yang, Bingcheng[1];Zhang, Feifang[1];Chu, Changhu[1];Liang, Xinmiao[1,2]

机构：[1]E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China;[2]Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China

年份：2012

卷号：137

期号：7

起止页码：1624

外文期刊名：ANALYST

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000301056100017)】；

基金：This research was sponsored by National Natural Science Foundation of China (No. 21075038, 21177040), the Shanghai Pujiang Program (No. 10PJ1402900), the Ministry of Science and Technology of China (2009BADB9B02) and the Fundamental Research Funds for the Central Universities.

语种：英文

摘要：A silica based amino stationary phase was prepared by immobilization of propargylamine on azide-silica via click chemistry. This readily prepared click amino stationary phase demonstrated good selectivity in separation of common inorganic anions under ion chromatography (IC) mode, and the triazole ring in combination with free amino group was observed to play a major role for separation of the anions examined. On the other hand, the stationary phase also showed good hydrophilic interaction liquid chromatography (HILIC) properties in the separation of polar compounds including nucleosides, organic acids and bases. The retention mechanism was found to match well the typical HILIC retention.