文献类型：期刊文献

英文题名：Cu-catalyzed mild and efficient oxidation of THβCs using air: Application in practical total syntheses of perlolyrine and flazin

作者：Zheng, Bo[1]; Trieu, Tien Ha[1]; Meng, Tian-Zhuo[1]; Lu, Xia[1]; Dong, Jing[1]; Zhang, Qiang[1]; Shi, Xiao-Xin[1]

机构：[1] Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology, 130 Mei-Long Road, Shanghai, 200237, China

年份：2018

卷号：8

期号：13

起止页码：6834

外文期刊名：RSC Advances

收录：EI(收录号：20180804822219)

语种：英文

外文关键词：Catalysis - Copper compounds - Pyridine

摘要：A mild, efficient and environmentally benign method for synthesis of aromatic β-carbolines via Cu(ii)-catalyzed oxidation of 1,2,3,4-tetrahydro-β-carbolines (THβCs) was developed, in which air (O2) was used as the clean oxidant. This method has advantages such as environmentally friendliness, mildness, very good tolerance of functional groups, high yielding and easy experiment operation. In addition, this new methodology was successfully applied in the efficient and practical total syntheses of β-carboline alkaloids perlolyrine and flazin. ? The Royal Society of Chemistry 2018.