文献类型：期刊文献

英文题名：Stimuli-Responsive Peptide Self-Assembly to Construct Hydrogels with Actuation and Shape Memory Behaviors

作者：Xiang, Yanxin[1,2];Liu, Can[1,2];Ma, Shinan[1,2];Wang, Xiaoting[1,2];Zhu, Linyong[1,2,3];Bao, Chunyan[1,2,3]

机构：[1]East China Univ Sci & Technol, Frontiers Sci Ctr Materiobiol & Dynam Chem, Inst Fine Chem, Sch Chem & Mol Engn,Key Lab Adv Mat,Feringa Nobel, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Feringa Nobel Prize Scientist Joint Res Ctr, Frontiers Sci Ctr Materiobiol & Dynam Chem, Inst Fine Chem,Joint Int Res Lab Precis Chem & Mol, Shanghai 200237, Peoples R China;[3]East China Univ Sci & Technol, Shanghai Frontiers Sci Ctr Optogenet Tech Cell Met, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China

年份：2023

卷号：33

期号：34

外文期刊名：ADVANCED FUNCTIONAL MATERIALS

收录：;EI(收录号：20231914063120);WOS:【SCI-EXPANDED(收录号:WOS:000981453700001)】；

基金：This work was supported by Shanghai Sci. Tech. Comm. (21ZR1415500), National Key Research and Development Project (2019YFA0110500), and Shanghai Frontier Science Research Base of Optogenetic Techniques for Cell Metabolism (Shanghai Municipal Education Commission, grant 2021 Sci & Tech 0328). The authors thank the Research Centre of Analysis and Test of East China University of Science and Technology for the help with the characterization.

语种：英文

外文关键词：hydrogel actuators; intelligent biomaterials; peptide self-assembly; stimulus responsiveness

摘要：Hydrogel actuators, capable of generating reversible deformation in response to external stimulus, are widely considered as new emerging intelligent materials for applications in soft robots, smart sensors, artificial muscles, and so on. Peptide self-assembly is widely applied in the construction of intelligent hydrogel materials due to their excellent stimulus response. However, hydrogel actuators based on peptide self-assembly are rarely reported and explored. In this study, a pH-responsive peptide (MA-FIID) is designed and introduced into a poly(N-isopropyl acrylamide) backbone (PNIPAM) to construct bilayer and heterogeneous hydrogel actuators based on the assembly and disassembly of peptide molecules under different pH conditions. These peptide-containing hydrogel actuators can perform controllable bending, bucking, and complex deformation under pH stimulation. Meanwhile, the Hofmeister effect of PNIPAM hydrogels endows these peptide-containing hydrogels with enhanced mechanical strength, ionic stimulus response (CaCl2), and excellent shape-memory property. This work broadens the application of supramolecular self-assembly in the construction of intelligent hydrogels, and also provides new inspirations for peptide self-assembly to construct smart materials.