文献类型：期刊文献

英文题名：Occurrence and reduction of antibiotic resistance genes in conventional and advanced drinking water treatment processes

作者：Hu, Yaru[1];Zhang, Tianyang[1,2];Jiang, Lei[3];Luo, Yi[4];Yao, Shijie[1];Zhang, Dong[3];Lin, Kuangfei[1];Cui, Changzheng[1,2]

机构：[1]East China Univ Sci & Technol, Sch Resources & Environm Engn, State Environm Protect Key Lab Environm Risk Asse, Shanghai 200237, Peoples R China;[2]Shanghai Inst Pollut Control & Ecol Secur, Shanghai 200092, Peoples R China;[3]Natl Engn Res Ctr Urban Water Resources, Shanghai 200082, Peoples R China;[4]Nankai Univ, Key Lab Pollut Proc & Environm Criteria, Coll Environm Sci & Engn,Minist Educ, Tianjin Key Lab Environm Remediat & Pollut Contro, Wei Jin Rd 94, Tianjin 300071, Peoples R China

年份：2019

卷号：669

起止页码：777

外文期刊名：SCIENCE OF THE TOTAL ENVIRONMENT

收录：;EI(收录号：20191206652029);WOS:【SCI-EXPANDED(收录号:WOS:000463663500075)】；

基金：This work was supported by the National Water Pollution Control and Management Technology Major Projects (No. 2017ZX07402003), Shanghai Municipal Science and Technology Commission (No. 16DZ1204703) and Open Project of State Key Laboratory of Urban Water Resource and Environment (No. QA201612), Shanghai Sailing Program (No. 18YF1406000), China Postdoctoral Science Foundation (No. 2017M621391) and the Fundamental Research Funds for the Central Universities (No. 222201814055).

语种：英文

外文关键词：Antibiotic resistance genes (ARGs); ARG reduction; Ozonation; Chlorination; Drinking water treatment plant (DWTP)

摘要：Antibiotic resistance is extensively detected in drinking water sources, threatening its safety and human health, which deserves further attention to the removal of antibiotic resistance genes (ARGs) in the drinking water system. In this study, the occurrence and reduction of integrase gene intI1 and forty-one ARG subtypes, which confers resistance to six antibiotic classes (beta-lactam, aminoglycoside, macrolide, tetracycline, sulfonamide, and quinolone), were investigated in a drinking water treatment plant (DWTP). Seventeen ARG subtypes with absolute concentrations ranging from 1.4 x 10(0) to 7.3 x 10(5) and 3.9 x 10(4) genes/mL (intI1) were detected in the raw water; and sul1 and sul2 were the two dominant ARG subtypes. Overall, the whole DWTPs achieved 0.03-2.4 log reduction of ARGs compared with those presented in raw water. The reduction efficiencies of sul1, strA, and intI1 were the highest (1.0-2.4 log) in both conventional and advanced processes. However, the levels of sul1, sul2, and ermC still remained high (1.3 x 10(0)-1.9 x 10(4) genes/mL) in finished water. The treatment units, including pre-flocculation/sedimentation/sand filtration, and ozonation units, were beneficial for the reduction of ARGs, which was mostly ascribed to the decline in biomass and the strong oxidizing properties of ozone. However, the reduction effect was subsequently counteracted by the granular activated carbon and chlorination units. This study provides basic data for ARG pollution in the drinking water system, and suggests that ARGs persist in drinking water, even after conventional chlorination or advanced treatment processes, highlighting the need for new and efficient water purification technologies. (C) 2019 Elsevier B.V. All rights reserved.