文献类型：期刊文献

英文题名：High-Performance Quinoline-Malononitrile Core as a Building Block for the Diversity-Oriented Synthesis of AIEgens

作者：Guo, Zhiqian[1,2];Yan, Chenxu[1,2];Zhu, Wei-Hong[1,2]

机构：[1]East China Univ Sci & Technol, Feringa Nobel Prize Scientist Joint Res Ctr, Shanghai Key Lab Funct Mat Chem, Key Lab Adv Mat,Inst Fine Chem,Sch Chem & Mol Eng, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Feringa Nobel Prize Scientist Joint Res Ctr, Joint Int Res Lab Precis Chem & Mol Engn, Shanghai Key Lab Funct Mat Chem,Inst Fine Chem,Sc, Shanghai 200237, Peoples R China

年份：2020

卷号：59

期号：25

起止页码：9812

外文期刊名：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

收录：;EI(收录号：20201208313631);WOS:【SCI-EXPANDED(收录号:WOS:000537909700002)】；

语种：英文

外文关键词：aggregation-induced emission; bioimaging; fluorescence probes; near-infrared; quinoline-malononitrile

摘要：In vivo fluorescent monitoring of physiological processes with high-fidelity is essential in disease diagnosis and biological research, but faces extreme challenges due to aggregation-caused quenching (ACQ) and short-wavelength fluorescence. The development of high-performance and long-wavelength aggregation-induced emission (AIE) fluorophores is in high demand for precise optical bioimaging. The chromophore quinoline-malononitrile (QM) has recently emerged as a new class of AIE building block that possesses several notable features, such as red to near-infrared (NIR) emission, high brightness, marked photostability, and good biocompatibility. In this minireview, we summarize some recent advances of our established AIE building block of QM, focusing on the AIE mechanism, regulation of emission wavelength and morphology, the facile scale-up and fast preparation for AIE nanoparticles, as well as potential biomedical imaging applications.