文献类型：专利

英文题名：Dual-mode contrast medium for medical imaging diagnosis, comprises core-shell type structure comprising inner core made of fluorescence imaging copper-indium sulfide quantum dot optical probe material, and outer shell

作者：ZHU Y;LI X;ZOU W;YANG X;LIN B

机构：[1]UNIV EAST CHINA SCI & TECHNOLOGY

申请号：CN103110964-B

公开日：2015-04-22

语种：英文

收录：DERWENT

摘要：NOVELTY - A dual-mode contrast medium comprises a core-shell type structure comprising inner core and outer shell. The core is fluorescence imaging copper-indium sulfide quantum dot optical probe. The shell is doped with divalent manganese ions and contains organic ligand. USE - Dual-mode contrast medium is used for medical imaging diagnosis. ADVANTAGE - The medium is free from pollutants and is prepared efficiently and economically, and has high fluorescence and magnetic resonance imaging. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for preparation of dual-mode contrast medium, which involves adding copper salts, indium salts and lauryl mercaptan to a reactor which is filled with a non-polar organic solvent, reacting and obtaining uniform copper-indium sulfide colloidal solution, adding a precursor solution of zinc and a precursor solution of manganese, and reacting and obtaining quantum-dot colloidal solution, adding extracting agent for extracting obtained quantum dots and obtaining quantum dots with the core-shell structure, and dispersing in the non-polar organic solvent, and adding mercaptan acid, and carrying out ligand exchange.