文献类型：期刊文献

英文题名：Asymmetric [3+2] annulation of allenes with maleimides catalyzed by dipeptide-derived phosphines: facile creation of functionalized bicyclic cyclopentenes containing two tertiary stereogenic centers

作者：Zhao, Qianyi[1,2];Han, Xiaoyu[3,4];Wei, Yin[5];Shi, Min[1,2,5];Lu, Yixin[1,2,3,4]

机构：[1]E China Univ Sci & Technol, Key Lab Adv Mat, Shanghai 200237, Peoples R China;[2]E China Univ Sci & Technol, Inst Fine Chem, Shanghai 200237, Peoples R China;[3]Natl Univ Singapore, Inst Life Sci, Dept Chem, Singapore 117543, Singapore;[4]Natl Univ Singapore, Med Chem Program, Inst Life Sci, Singapore 117543, Singapore;[5]Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China

年份：2012

卷号：48

期号：7

起止页码：970

外文期刊名：CHEMICAL COMMUNICATIONS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000299649900007)】；

基金：We thank the Shanghai Municipal Committee of Science and Technology (08dj1400100-2), National Basic Research Program of China (973)-2010CB833302, the Fundamental Research Funds for the Central Universities and the National Natural Science Foundation of China for financial support (21072206, 20872162, 20672127, 20732008, 20821002 and 20702013).

语种：英文

摘要：D-Threonine-L-tert-leucine-derived bifunctional phosphine, Cat. 11, catalyzed highly enantioselective [3+2] annulation of maleimides with allenes has been disclosed, allowing the synthesis of optically active functionalized bicyclic cyclopentenes containing two tertiary stereogenic centers in good to high yields along with good to high enantioselectivities.