文献类型：期刊文献

英文题名：Tailoring Plasmonic Nanostructures for Optimal SERS Sensing of Small Molecules and Large Microorganisms

作者：Xu, Jiajie[1,2];Zhang, Lei[1];Gong, Heng[2];Homola, Jiri[3];Yu, Qiuming[1]

机构：[1]Univ Washington, Dept Chem Engn, Seattle, WA 98195 USA;[2]E China Univ Sci & Technol, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China;[3]Acad Sci Czech Republic, Inst Photon & Elect, CR-18251 Prague, Czech Republic

年份：2011

卷号：7

期号：3

起止页码：371

外文期刊名：SMALL

收录：;EI(收录号：20110713658799);WOS:【SCI-EXPANDED(收录号:WOS:000287607000013)】；

基金：This work was supported in part by the University of Washington (UW) faculty start-up funds. J.J. Xu acknowledges a fellowship from the China Scholarship Council. Nanofabrication and SERS studies were performed at the Nanotech User Facility, the UW site of the National Nanotechnology Infrastructure Network (NNIN) supported by the NSF.

语种：英文

外文关键词：Plasmonics - Finite difference time domain method - Gold - Metallic films - Nanostructures - Electric fields - Raman scattering - Surface scattering - Molecules

摘要：Local electric fields can be tuned dramatically by varying the diameter of quasi-3D gold plasmonic nanostructure arrays, as indicated by 3D finite-difference time-domain calculations. Utilizing quasi-3D arrays that exhibit a maximum electric field intensity (i.e., a "hot" spot) either at the bottom (gold nanodisks) or on the top (gold film patterned with nanoholes), the optimal surface-enhanced Raman scattering (SERS) sensitivity for the detection of small molecules or large microorganisms can be achieved. The precisely fabricated and optimized SERS-active quasi-3D nanostructure arrays make it possible to quantitatively and reproducibly detect chemical and biological species using SERS, leading to a new sensing platform with molecular specificity based on SERS for many important applications.