文献类型：期刊文献

中文题名：气-液界面上的Gemini表面活性剂/DNA复合膜

英文题名：Gemini Surfactant/DNA Complex Film on Air-Water Interface

作者：李蓉[1,2];陈启斌[1];刘洪来[1]

机构：[1]华东理工大学结构可控先进功能材料及其制备教育部重点实验室,上海200237;[2]江南大学生态纺织教育部重点实验室,江苏无锡214122

年份：2013

卷号：39

期号：4

起止页码：399

中文期刊名：华东理工大学学报（自然科学版）

外文期刊名：Journal of East China University of Science and Technology

收录：CSTPCD;;Scopus;北大核心:【北大核心2011】；CSCD:【CSCD2013_2014】；

语种：中文

中文关键词：Gemini表面活性剂;DNA;LB膜;复合膜

外文关键词：Gemini surfactant ; DNA; LB film; complex film

摘要：用Langmuir-Blodgett(LB)膜技术和原子力显微镜探讨平衡时间、盐浓度和连接基团长度对气-液界面上阳离子型Gemini表面活性剂([C18H37(CH3)2N+-(CH2)s-N+(CH3)2C18H37]·2Br-,简写成18-s-18,s=3、4、6、8、10、12)与DNA分子之间相互作用的影响。结果表明,表面活性剂与DNA分子之间的相互作用达到平衡时需较长时间;随着盐浓度的增加,盐的屏蔽作用增大,致使表面活性剂与DNA分子之间的相互作用减弱;当连接基团为刚性(s=3、4)时,分子间的空间位阻较小,Gemini表面活性剂/DNA复合膜主要形成纤维结构;而当连接基团为柔性(s≥8)时,分子间的位阻效应增大,则主要形成片状聚集体。
The influence of equilibrium time, concentration of salt and spacer length on the interaction between the cationic Gemini surfactant （[[C18H37（CH3）2N-_（CH2）,-N＋（CH3）2C18H37]·2Br-, abbreviated as 18-s-18,s=3.4.6.8.10,12） and DNA on the air-water interface were investigated using LB film and AFM. We found that for the interaction between the Gemini surfactant and DNA it takes a long time to achieve balance. The interaction between Gemini surfactant and DNA declined with the increase of salt concentration, because the addition of salt shielded the surface charge of DNA molecules. When spacer is rigid （s=3 and 4）, the intermolecular steric hindrance is relatively small, and the main morphology of Gemini/DNA complex film is parallel fibril . When spacer is flexible （s=8）, the intermolecular steric hindrance increased with the increasing of spacer length, and the main morphology becomes sheet aggregates.