文献类型：期刊文献

英文题名：An Ultrasensitive Plasmonic Nanosensor for Aldehydes

作者：Li, Meng[1,2];Shi, Lei[3];Xie, Tao;Jing, Chao[2,4];Xiu, Guangli[1];Long, Yi-Tao[2]

机构：[1]East China Univ Sci & Technol, Sch Chem & Mol Engn, State Environm Protect Key Lab Risk Assessment &, 130 Meilong Rd, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Sch Chem & Mol Engn, Key Lab Adv Mat, 130 Meilong Rd, Shanghai 200237, Peoples R China;[3]Shanghai Qingpu Water Author, 35 Xidayingangyi Rd, Shanghai 201799, Peoples R China;[4]Tech Univ Munich, Phys Dept E20, James Franck Str 1, D-85748 Garching, Germany

年份：2017

卷号：2

期号：2

起止页码：263

外文期刊名：ACS SENSORS

收录：;EI(收录号：20181705049360);WOS:【SCI-EXPANDED(收录号:WOS:000395047000012)】；

基金：This research was supported by the Science Fund for Creative Research Groups (21421004), the National Natural Science Foundation of China (21327807), the Program of Shanghai Subject Chief Scientist (15XD1501200), the Programme of Introducing Talents of Discipline to Universities (B16017), and the State Key Laboratory of Analytical Chemistry for Life Science Open Foundation (SKLACLS1512).

语种：英文

外文关键词：glucose sensor; plasmonic; nanoparticles; ultrasensitive; anti-interference

摘要：Glucose is the most common but important aldehyde, and it is necessary to create biosensors with high sensitivity and antiinterference to detect it. Under the existence of silver ions and aldehyde compounds, single gold nanoparticles and freshly formed silver atoms could respectively act as core and shell, which finally form a core shell structure. By observing the reaction between glucose and Tollens' reagent, metallic silver was found to be reduced on the surface of gold nanoparticles and formed Au@Ag nanoparticles that lead to a direct wavelength shift. Based on this principle and combined with in situ Ag plasmon resonance scattering spectra, a plasmonic nanosensor was successfully applied in identifying aldehyde compounds with excellent sensitivity and specificity. This ultrasensitive sensor was successfully further utilized to detect blood samples, exhibiting good anti-interference ability and great promise for future clinical application. glucose in mice serum