文献类型：期刊文献

英文题名：Hydrogels assembled by inclusion complexation of poly(ethylene glycol) with alpha-cyclodextrin

作者：Wang, Jie[1];Li, Li[1];Zhu, Yunying[1];Liu, Peng[1];Guo, Xuhong[1]

机构：[1]E China Univ Sci & Technol, State Key Lab Chem Engn, Shanghai 200237, Peoples R China

年份：2009

卷号：4

期号：5

起止页码：544

外文期刊名：ASIA-PACIFIC JOURNAL OF CHEMICAL ENGINEERING

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000271441300007)】；

基金：We gratefully acknowledge NSFC Grant 20774030, Shanghai Shuguang Plan Project 06SG35, Shanghai Pujiang Talent Project 08PJ14036, and 07PJ14022 for support of this work.

语种：英文

外文关键词：alpha-cyclodextrin; poly(ethylene glycol); inclusive complexation; hydrogel

摘要：Polymeric hydrogels were prepared based on the inclusive complexation between alpha-cyclodextrin (alpha-CD) and poly(ethylene glycol) (PEG). Because the rheological property of a thermodynamic stable hydrogel should be gap-independent, it is found in this work that the uniformed hydrogel can be distinguished from gel-like aggregation by changing the plate gap during the rheological measurement. By this rheological method it is determined that suitable storage duration is necessary for the preparation of uniform hydrogels. However, the sonication technique after mixing CD and PEG solutions or increasing PEG concentration can shorten the time to form stable hydrogels. Moreover, the molecular weight of PEG should be high enough (>= 8000 g/mol) for sol-gel transition. The higher the molecular weight of PEG is, the longer storage time is needed to obtain a uniform hydrogel. From the observation by differential scanning calorimetry (DSC) and X-ray diffraction (XRD) of prepared hydrogels, we concluded that the driving force of networks should be attributed to the crystallization of complexed alpha-CDs in the alpha-CD/PEG pseudo-polyrotaxanes. (C) 2009 Curtin University of Technology and John Wiley & Sons, Ltd.