文献类型：会议论文

英文题名：Synthesis and characteristic of molecularly imprinted polymer immobilized mesoporous silica sphere for selective binding of S-naproxen

作者：Bing, Nai-Ci[1];Tian, Zhen[1];Chen, Sheng-Wen[1];Li, Qing-Hua[1];Xu, Zhen-Liang[2]

机构：[1]Shanghai Second Polytech Univ, Dept Environm Engn, Shanghai 201209, Peoples R China;[2]E China Univ Sci & Technol, Dept Engn Res Ctr, Shanghai 200237, Peoples R China

会议论文集：International Conference on Multifunctional Materials and Structures

会议日期：JUL 28-31, 2008

会议地点：Hong Kong, PEOPLES R CHINA

语种：英文

外文关键词：molecularly imprinted polymer; surface imprinting; mesoporous silica sphere; S-naproxen

摘要：Molecularly imprinted composite materials (PM) selective to S-naproxen were prepared in the surface of mesoporous silica sphere (SBA-15) by surface imprinting technique. FT-IR, SEM and surface area analysis were used to study the structural morphology of PM and MIPs particles and probe the incorporation of polymer into the SBA-15 framework. The results revealed that PM showed better binding affinity and selectivity to the template molecule than MIPs and the maximum saturated binding capacity of PM to S-naproxen and R-naproxen was about 10.3332 and 6.0063 mu mol.g(-1). Meanwhile, we achieve a reference strategy for the development of molecularly imprinting polymer for drugs and to handle forms in certain applications Such as chromatographic stationary phases for chiral separations.