文献类型：期刊文献

中文题名：响应面分析法优化艾叶粗多糖提取工艺的研究

英文题名：Optimium extraction of polysaccharides from folium Artemisia argyi by response surface methodology

作者：沈霞[1];张艳红[1];袁慧慧[1];蓝闽波[1,2]

机构：[1]华东理工大学分析测试中心,上海200237;[2]华东理工大学超细材料制备与应用教育部重点实验室,上海200237

年份：2010

卷号：32

期号：1

起止页码：48

中文期刊名：中成药

外文期刊名：Chinese Traditional Patent Medicine

收录：CSTPCD;;北大核心:【北大核心2008】；CSCD:【CSCD2011_2012】；

基金：上海市科委中药现代化专项基金(08DZ1974000)

语种：中文

中文关键词：艾叶多糖;提取;响应面分析;优化

外文关键词：folium Artemisia argyi polysaccharide; extraction; response surface methodology; optimization

摘要：目的:利用响应面分析法(Response Surface Methodology,RSM)对艾叶多糖提取工艺进行优化。方法:在单因素实验基础上选取实验因素与水平,根据中心组合(Box-Benhnken)实验设计原理采用三因素三水平的响应面分析法,以获得多元二次线性回归方程,以多糖提取率为响应值作响应面和等高线。结果:确定了水浸提艾叶多糖最佳工艺条件:浸提温度99℃,浸提时间2.3h,水料比20。结论:在此条件下,艾叶多糖的提取率可达3.017%,与理论预测值3.096%的相对误差为2.6%。
AIM： To optimize the extraction of foliutn Artemisia argyi polysaccharides by the use of response surface methodoloy. METHODS ： Experiment factors and levels were first selected on the ground of one factor test. Along with the central composite experimental design principles,the response surface methodoloy with three factors and three levels was adopted in search of multiple quadratic linear regression. Response surface and contour were finally chosen as the extraction rate and the response value respectively. RESULTS： The optimum extraction conditions of the polysaccharides from folium Artemisia argyi were concluded as follows ： extraction temperature was at 99 ℃, extraction time was 2.3 hours, ratio of 20. CONCLUSION ： Under these conditions, the yield of folium Artemisia argyi polysaccarides is up to 3. 017% , extraction rate of the predictive best polysaccharides is 3. 096%, and the relative error is 2.6%.