文献类型：期刊文献

英文题名：Effectiveness research of deep brain stimulation operation for patients with Parkinson's disease based on polar coordination system with varied origin

作者：Wang, Min[1]; Wang, Bei[1]; Zou, Junzhong[1]; Zhang, Jian[1]; Nakamura, Masatoshi[2]

机构：[1] Department of Automation, School of Information Science and Engineering, East China University of Science and Technology, Shanghai 200237, China; [2] Department of Advanced System Control Engineering, Saga University, Saga 840-8502, Japan

年份：2011

卷号：2

起止页码：730

外文期刊名：Proceedings - 2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011

收录：EI(收录号：20120314690549)

语种：英文

外文关键词：Neurodegenerative diseases - Clinical research - Diagnosis - Neurosurgery

摘要：Parkinson's disease (PD) is a common disease of central nervous system among the elderly, and its complex symptoms bring up some difficulties for the clinical diagnosis. And Deep Brain Stimulation (DBS) is an effective treatment method for patients with Parkinson's disease. In this study, a method based on polar coordination system with varied origin was proposed to quantitatively evaluate the availability of DBS operation for patients with Parkinson's disease. Totally, seven patients with Parkinson's disease were participated in the spiral drawing experiment and their scores under Unified Parkinson's disease Rating Scale (UPDRS) were also recorded. According to the characteristics of hand movement in spiral drawing, a set of parameters were defined and calculated before and after DBS operation. Compared with the UPDRS scores, experimental results showed that this method of evaluation was consistent with the clinical diagnosis. The proposed method based on polar coordinate system with varied origin is effective in clinical diagnosis, and it provides a basis for quantitative evaluating the effectiveness of surgery and treatment. ? 2011 IEEE.