文献类型：专利

英文题名：New modified sarsasapogenin derivative used in pharmaceutical composition for preparing drug for treating Alzheimer's disease

作者：MA L;PAN H;XU T;YANG Y;WANG R;ZHAO J;ZHOU N;ZHANG J;ZHANG Z;YIN H;XIONG J;XU L

机构：[1]UNIV EAST CHINA SCI & TECHNOLOGY

申请号：CN104513289-B

公开日：2017-12-22

语种：英文

收录：DERWENT

摘要：NOVELTY - A modified sarsasapogenin derivative (I) or (II), is new. USE - New modified sarsasapogenin derivative is used in pharmaceutical composition for preparing drug for treating Alzheimer's disease (all claimed). DETAILED DESCRIPTION - A modified sarsasapogenin derivative of formula (I) or (II), is new. R1=group chosen from group of formulae (i)-(vi); R2-R4=1-8C linear or branched alkyl or optionally substituted aryl; R5,R6=H; R7=H, 1-8C linear or branched alkyl or optionally substituted aryl; R'=-R2', -O-R3', -X-C(=O)-R4' or -N(-R5')(-R6'); R2'=halo; R3'=H, 1-8C linear or branched alkyl or optionally substituted aryl; X=O or NH; R4'=1-8C linear or branched alkyl, optionally substituted aryl or heteroaryl; R5'=H;and R6'=linear or branched substituted 1-8C alkyl.