文献类型：期刊文献

英文题名：Low-Toxic and Nonirritant Biosurfactant Surfactin and its Performances in Detergent Formulations

作者：Fei, Dan[1,2];Zhou, Guang-Wei[1,2];Yu, Zhou-Qiang[1,2];Gang, Hong-Ze[1,2];Liu, Jin-Feng[1,2];Yang, Shi-Zhong[1,2];Ye, Ru-Qiang[1,2];Mu, Bo-Zhong[1,2,3]

机构：[1]East China Univ Sci & Technol, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Sch Chem & Mol Engn, Shanghai 200237, Peoples R China;[3]Shanghai Collaborat Innovat Ctr Biomfg Technol, Shanghai 200237, Peoples R China

年份：2020

卷号：23

期号：1

起止页码：109

外文期刊名：JOURNAL OF SURFACTANTS AND DETERGENTS

收录：;EI(收录号：20194407596368);WOS:【SCI-EXPANDED(收录号:WOS:000489520900001)】；

基金：This research was supported by the National High Technology Research and Development Program of China (2013AA064403), the Fundamental Research Funds for the Central Universities of China (22221818014), and Research Program of State Key Laboratory of Bioreactor Engineering.

语种：英文

外文关键词：Surfactin; Eco-friendly; Nonirritant; Low-toxic; Detergent

摘要：Developing eco-friendly, nonirritant, low-toxic, and high-efficient surface active ingredients for detergents is an ongoing challenge in the detergent field. Surfactin is one of the representative lipopeptides produced by microorganisms. In this article, we report the surfactin isolated from cell-free broth of Bacillus subtilis HSO121 and purified by reversed-phase high-performance liquid chromatography for detergent formulations. The biodegradability, acute dermal irritation, acute oral toxicity (LD50 and LC50), surface activity, washing efficiency, and compatibility with hard water of the purified biosurfactant surfactin have been studied to explore the feasibility for applications of the surfactin in detergents. Acute oral toxicity tests (LD50 > 5000 mg kg(-1), LC50 > 1000 mg kg(-1)) and skin irritation tests (PII = 0) indicate that the surfactin is a low-toxic and nonirritant ingredient for detergent formulation. Moreover, the surfactin shows excellent surface and interfacial properties of emulsification and wettability, high compatibility, and stability in a wide range of temperatures, pH, and hard water and acceptable properties in biodegradability and foaming ability, which suggests that the biosurfactant surfactin is a promising ingredient for detergent formations in our daily life and for industrial applications.