文献类型：期刊文献

英文题名：Highly enantioselective intramolecular Rauhut-Currier reaction catalyzed by chiral thiourea-phosphine

作者：Zhao, Xuan[1,2];Gong, Jing-Jing[1,2];Yuan, Kui[1,2];Sha, Feng[1,2];Wu, Xin-Yan[1,2,3]

机构：[1]E China Univ Sci & Technol, Key Lab Adv Mat, Shanghai 200237, Peoples R China;[2]E China Univ Sci & Technol, Inst Fine Chem, Shanghai 200237, Peoples R China;[3]Nankai Univ, State Key Lab Elementoorgan Chem, Tianjin 300071, Peoples R China

年份：2015

卷号：56

期号：19

起止页码：2526

外文期刊名：TETRAHEDRON LETTERS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000353751000034)，CCR-EXPANDED(收录号:WOS:000353751000034)】；

基金：We are grateful for the financial support from the National Natural Science Foundation of China (21242007, 21102043) and the Fundamental Research Funds for the Central Universities.

语种：英文

外文关键词：Enantioselective catalysis; Rauhut-Currier reaction; Thiourea-phosphine; Bis(enones)

摘要：A highly enantioselective intramolecular Rauhut-Currier reaction of bis(enones) has been developed by employing bifunctional thiourea-phosphine organocatalysts based on a chiral cyclohexane scaffold. In the presence of 10 mol % of thiourea-phosphine 1h, the desired products were obtained in good yields with up to 99% ee. (C) 2015 Elsevier Ltd. All rights reserved.