文献类型：期刊文献

中文题名：聚类分析在红霉素摇瓶培养基无机盐分析中的应用

英文题名：Application of cluster analysis on inorganic salt of the erythromycin fermentation medium

作者：罗致强[1];宫衡[1];付水林[1]

机构：[1]华东理工大学生物反应器工程国家重点实验室,上海200237

年份：2006

卷号：31

期号：3

起止页码：172

中文期刊名：中国抗生素杂志

外文期刊名：Chinese Journal of Antibiotics

收录：CSTPCD;;Scopus;北大核心:【北大核心2004】；CSCD:【CSCD2011_2012】；

语种：中文

中文关键词：红霉素;有机氮源;聚类分析;无机盐;无机磷

外文关键词：Erythromycin; Organic nitrogen source; Cluster analysis; Inorganic salt; Inorganic phosphor

摘要：红色糖多孢菌的摇瓶培养基中使用不同有机氮源时红霉素的效价明显不同。通过对培养基中不同有机氮源所含无机盐的聚类分析,发现无机磷为影响红霉素效价的主要因素。培养基中无机磷含量高了会显著抑制红霉素的生物合成。
The production of erythromycin in the shake flask was significantly influenced by adding different kinds of organic nitrogen source. With the use of cluster analysis method, the effect of inorganic salt in the different organic nitrogen source were analyzed. Result showed that the inorganic phosphor was the key factor affecting the erythromycin production. The production of erythromycin decreased remarkably with the high content of inorganic phosphor in the fermentation medium.