文献类型：期刊文献

英文题名：Facile synthesis of ultrathin two-dimensional graphene-like CeO2-TiO2mesoporous nanosheet loaded with Ag nanoparticles for non-enzymatic electrochemical detection of superoxide anions in HepG2 cells

作者：Wang, Zhenxing[1];Zhao, Hongli[1];Gao, Qianmei[1];Chen, Kaicha[1];Lan, Minbo[1,2]

机构：[1]East China Univ Sci & Technol, Sch Chem & Mol Engn, Shanghai Key Lab Funct Mat Chem, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Res Ctr Anal & Test, Shanghai 200237, Peoples R China

年份：2021

卷号：184

外文期刊名：BIOSENSORS & BIOELECTRONICS

收录：;EI(收录号：20211610237641);WOS:【SCI-EXPANDED(收录号:WOS:000648512000003)】；

基金：This work was supported by the Natural Science Foundation of Shanghai (19ZR1412000), the Science and Technology Commission of Shanghai Municipality (STCSM, 20520712500), and the Fundamental Research Funds for the Central Universities (50321102117022).

语种：英文

外文关键词：Two-dimensional; Metal oxides; Ag nanoparticles; Superoxide anions; Electrocatalytic reduction

摘要：Here we presented a new facile strategy to fabricate ultrathin two-dimensional (2D) metal oxide nanosheets, by using polydopamine-coated graphene (rGO@PDA) as a template under simplywet-chemicalconditions. Based on the strategy, graphene-like CeO2-TiO(2)mesoporousnanosheet (MNS-CeO2-TiO2) was prepared and was loaded with dispersive Ag nanoparticles (AgNPs) to obtain effective electrocatalysts (denoted asAg/MNS-CeO2-TiO2) forelectrochemical detectionof superoxide anion (O-2(center dot & minus;)). Characterizations demonstrated that MNS-CeO2-TiO(2)exhibited ultrathin thickness, larger specific surface area, andpore volumein comparison with its bulk counterpart. The above properties of MNS-CeO2-TiO(2)shorten electron transmission distance, promotes mass transfer, and is conducive to the dispersion of post-modified AgNPs. Therefore, the recommended Ag/MNS-CeO2-TiO(2)sensors (denoted asAg/MNS-CeO2-TiO2/SPCE) exhibited satisfactory properties, including the sensitivity of 737.1 mu Acm(& minus;2)mM(& minus;1), the detection limit of 0.0879 mu M (S/N=3), and good selectivity. Meanwhile, the sensors also successfully realized in the online monitoring of O(2)(center dot & minus;)released from HepG2 cells, meaning the prepared sensors had practical application potential towards the analysis of O(2)(center dot & minus;)in biological samples.