文献类型：会议论文

英文题名：A SIMPLE AND RELIABLE CONFIGURATION WITH NEEDLE VALVE FOR MANIPULATING FLOW IN MICROFLUIDIC CHIP

作者：Mu Xuan[1];Liang Qianglin[2];Hu Ping[2,3];Ren Kangning[2];Wang Yiming[2];Luo Guoan[1,2]

机构：[1]E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China;[2]Tsinghua Univ, Dept Chem, Key Lab Bioorgan Phosphorus Chem & Chem Biol, Minist Educ, Beijing 100084, Peoples R China;[3]East China Univ Sci & Technol, Coll Chem & Mol Engn, Shanghai 200237, Peoples R China

会议论文集：6th International Forum on Post-Genome Technologies

会议日期：SEP 17-18, 2009

会议地点：Beijing, PEOPLES R CHINA

语种：英文

外文关键词：Microfluidic chip; two phase flow; flow rate; laminar flow; bubble

摘要：This paper demonstrates a simple and reliable configuration to control fluid flows in microfluidic chip. Such configuration is easy to establish and remarkable inexpensive. The whole system costs about 15 USD (except water pump). Water pump provides power to drive water into chip. The combination of T - junction and needle valve offers reliable adjustment of vacuum level. Turning up the needle valve leads to the decreasing of vacuum level in the chip, and turning down the needle valve leads to the increasing the vacuum level. Vacuum level is linearly proportional to volumetric velocity. The precision of manual operation is 5 kPa. We successfully apply this configuration to adjust two kinds of two-phase laminar flow: air-ethanol and perfluorodecalin (PFD)-water. Under different flow rate, the flow pattern may falls into different regimes. The laminar flow of ethanol and air could transfer to bubble. However, the laminar flow of water and PFD was not affected by flow rate.